美发现肺有可能再生
http://www.100md.com
2001年2月7日
CHICAGO (Reuters) - It may be possible in the next few decades to fight a variety of lung diseases by regenerating human lung tissue, a researcher said on Tuesday.
``The ultimate goal for replacement of diseased lung tissue is to regrow a new functional lung,'' said Ronald Crystal of Weill Medical College at Cornell University. ``With the technology available to identify the genes that control lung growth, major advances in this area should occur in the next few decades.''
``It is only a matter of time before lung stem cells are identified,'' he added. ``While it is not clear which direction this research will take in regard to an organ as cellular and anatomically complex as the lung, the ability to reprogram lung growth is a goal worth pursuing.''
Crystal made the comments in an essay published in this week's Journal of the American Medical Association.
Such research is also worth pursuing, he said, because the number of donated human lungs available for transplant is likely to remain limited and transplants from other animals -- xenographs -- are not likely to increase the supply in the next quarter century.
Crystal also predicted that the genes involved in susceptibility to asthma will be defined and characterized in coming years, something that will better help victims of the disease avoid the its causes and open the way to ``new therapeutic targets to prevent and treat this disorder.'', 百拇医药
``The ultimate goal for replacement of diseased lung tissue is to regrow a new functional lung,'' said Ronald Crystal of Weill Medical College at Cornell University. ``With the technology available to identify the genes that control lung growth, major advances in this area should occur in the next few decades.''
``It is only a matter of time before lung stem cells are identified,'' he added. ``While it is not clear which direction this research will take in regard to an organ as cellular and anatomically complex as the lung, the ability to reprogram lung growth is a goal worth pursuing.''
Crystal made the comments in an essay published in this week's Journal of the American Medical Association.
Such research is also worth pursuing, he said, because the number of donated human lungs available for transplant is likely to remain limited and transplants from other animals -- xenographs -- are not likely to increase the supply in the next quarter century.
Crystal also predicted that the genes involved in susceptibility to asthma will be defined and characterized in coming years, something that will better help victims of the disease avoid the its causes and open the way to ``new therapeutic targets to prevent and treat this disorder.'', 百拇医药