阿斯匹林能有效降低女性卵巢癌的发生率
【摘要】发布在美国妇产科研究年会上的一项研究报告指出：隔天服用一次阿斯匹林有助于预防至少一种类型的癌症。对于女性，一周或者至少六个月内服用过三次阿斯匹林的人，比没有服用阿斯匹林的人有着较低的卵巢癌发生率。【全文】Study suggests aspirin cuts ovarian cancer riskBy Anne HardingNEW YORK, Mar 07 (Reuters Health) - An aspirin every other day could help keep at least one type of cancer away, results of a new study suggest. Women who took aspirin three times a week for at least 6 months had a lower risk of developing the most common form of ovarian cancer than those who did not, reported Dr. Arslan Akhmedkhanov of the New York University School of Medicine and colleagues on Wednesday at the Society of Gynecologic Oncologists' annual meeting in Nashville, Tennessee.The study had its limitations, Akhmedkhanov told Reuters Health, including the small number of women who were included and the lack of specific information on how much aspirin the women took and why they were taking it. For this reason, he said, women should not take aspirin to prevent ovarian cancer based on these findings. Larger studies are needed, he cautioned.Ovarian cancer is difficult to treat because it is rarely found in its early stages. According to the American Cancer Society, about 23,000 new cases of ovarian cancer are diagnosed annually, and 14,000 women will die of the disease each year.The causes of ovarian cancer are poorly understood, but the disease most often strikes women aged 65 and older, and in some cases may have a genetic component. Women with chronic inflammation of the pelvic area--for example, those who have endometriosis or pelvic inflammatory disease--have an increased risk of developing the disease, Akhmedkhanov told Reuters Health.Inflammation is the immune system's response to injury. When inflammation occurs, swelling, pain and fever result. While inflammation can help injured tissues to heal, it can also spiral out of control and damage tissues. Aspirin and related medications, known collectively as nonsteroidal anti-inflammatory drugs (NSAIDs), control inflammation by blocking the production of prostaglandins--chemicals that the body releases after injury.In the study, Akhmedkhanov and colleagues looked at the group of more than 14,000 women included in the New York University (NYU) Women's Health Study. They identified 68 women with epithelial ovarian cancer, the most common form of the disease, who had answered questions on their aspirin use. These women were matched to 680 cancer-free women who had also answered questions on aspirin use.Women who took aspirin for at least 6 months, at least three times a week, had a 40% lower epithelial ovarian cancer risk compared with non-aspirin users, the findings indicate.Evidence is mounting that taking aspirin regularly can help prevent colon cancer. Many people at risk of heart disease also take aspirin daily to guard against heart attack and stroke. But NSAIDs have risks, including an increased risk of bleeding, particularly in the stomach and intestines."The idea of this study was to spark interest in the role of aspirin in preventing cancers," Akhmedkhanov told Reuters Health. "We certainly hope this study will induce other individuals to look at its effects."He and his colleagues are now looking at the NYU Women's Health Study to see if there is a link between taking aspirin and reduction in lung cancer and uterine cancer., 百拇医药