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Dhea可治疗女性性功能障碍
http://www.100md.com 2001年7月26日 家庭医生医疗保健网
     最近召开的美国泌尿学会年会上的一项报告表明,女性由于雄激素不足导致的性功能障碍疾病可以通过脱氢表雄(甾)酮(DHEA)获到良好的治疗效果。

    研究人员给32名由于缺乏雄激素而导致性欲、性唤起低下和缺乏性高潮的妇女每天服用50毫克DHEA,5个月后,80%妇女的睾丸激素和DHEA水平恢复正常。根据女性性功能指数和性压力水平,大部份妇女反映自发性性欲显著增长,而达到性兴奋的时间显著缩短,同时对性有了更多的兴趣。

    绝大部份女性性功能障碍是由于缺乏DHEA,这一发现是医学界的一项意义重大的发现。DHEA是位于肾脏顶部的肾上腺分泌的产物,人体的DHEA水平通常会在20-30岁期间达到最高峰,随后逐渐降低。对于某些肾上腺激活不足的人来说,即使她们处于年轻时期,DHEA水平也很低。研究人员发现,雄激素对于女性性欲、性唤起和性感觉是必需的。

    对于因缺乏雄激素而导致性功能障碍的女性来说,DHEA似乎非常有效。但这种激素是处方药,没有医生的许可不能服用。同时,该药也有一些相关的副作用,比如会导致粉刺、毛发增多、油性皮肤以及增加乳腺癌危险等副作用,因此一定要在医生指导下服用。
, http://www.100md.com
    Hormone May Treat Female Sexual Dysfunction

    ANAHEIM, Calif. (Reuters Health) - Women with sexual dysfunction caused by a deficiency in the ``male‘‘ hormone androgen may benefit from treatment with dehydroepiandosterone (DHEA), according to a presentation given here over the weekend during the American Urological Association‘s annual meeting.

    DHEA is produced by the adrenal glands, which are located atop the kidneys. Normally, levels of DHEA in the body peak when a person is 20 to 30 years old, and then begin to decline gradually. However, in people with underactive adrenal glands, levels of the hormone are low, even in their youth.
, http://www.100md.com
    The researchers gave 32 women with diminished sexual interest, arousal and orgastic capabilities due to low androgen levels 50 milligrams per day of DHEA for an average of 5 months. In 80% of the women, the hormone treatment returned testosterone and DHEA levels to normal. On the Female Sexual Function Index and the Sexual Distress Scale, most of the women reported a significant increase in spontaneity and decreased time to achieve arousal. They also reported having more interest in sex.
, http://www.100md.com
    ``The field of female sexual medicine is very poorly studied,‘‘ Dr. Irwin Goldstein of Boston University School of Medicine, the study‘s lead author, told Reuters Health. The recognition that a significant number of women with sexual dysfunction have low DHEA values is a significant ``breakthrough,‘‘ he said. ``Androgens, we are finding, are required for sexual interest, arousal and sensation.‘‘

    DHEA appears to be ``most effective‘‘ in women with sexual dysfunction due to androgen deficiency, he said. Goldstein is concerned, however, that women might start taking DHEA without consulting their physician.

    While the hormone is available over the counter, he said, it should not be taken without medical evaluation. ``There are side effects associated with androgen use including acne, hair growth, oily skin, and we are worried about breast cancer as well,‘‘ he said. ``So it must be taken under physician management.‘‘, 百拇医药