十、国外动物疾病模型参阅表
疾病名称、动物、作者及年份
| (一)心血管系统 |
沙土鼠 |
Shakibi |
1969 | ||||||
| 1.动脉粥样硬化 |
海豚 |
Cray |
1974 | ||||||
| 小鼠 |
Hummel |
1962 |
3.心衰 |
||||||
| 大鼠 |
Thant |
1970 |
地鼠 |
Koletsky |
1977 |
Bajusz |
1969 | ||
| Imai |
1973 |
4.心肌病 |
|||||||
| 兔 |
Minick |
1973 |
猫 |
Zook |
1981 | ||||
| 小鼠 | Wigley | 1970 | |||||||
| Clarkson |
1961 |
(二)消化系统 | |||||||
| Wagner |
1973 | 1.胃溃疡 | |||||||
| 沙土鼠 |
Wexler |
1971 |
猪 |
Norton |
1972 | ||||
| 狗 |
Malmros |
1968 |
Muggenberg |
1964 | |||||
| 猪 |
Gottlieb |
1954 |
牛 |
Lde |
1964 | ||||
| Glorentin |
1968 |
2.食道驰缓 | |||||||
| Lee |
1971 | 狗 |
Clifford |
1973 | |||||
| 猫 |
Lindsay |
1955 |
Osborne |
1967 | |||||
| 灵长类 |
Wisster |
1977 |
小鼠 |
Fernandes |
1968 | ||||
| Gresham |
1976 | 3.结肠炎 |
|||||||
| Newman |
1974 |
狗 |
Rubin |
1973 | |||||
| 2.高血压 |
Faman |
1974 |
Van Kruiningen |
1972 | |||||
| 大鼠 |
Okamoto |
1974 |
|||||||
| 灵长类 |
London |
1972 |
猪 |
Johnson |
1958 | ||||
| Semlana |
1965 |
8.脊柱裂、腭裂 |
|||||||
| 大鼠 |
Margolis |
1968 |
小鼠 |
Bornstein |
1970 | ||||
| 鸭 |
Fabricant |
1957 |
Kalter |
1971 | |||||
| 7.胰腺炎 | 兔 |
Crary | 1966 | ||||||
| 狗 |
Thordal |
1956 |
灵长类 |
Padget |
1972 | ||||
| 8.胆石症、胆囊炎 | 狗 |
Sherwoos | 1971 | ||||||
| 牛 |
Mcgavin |
1962 |
9.侏儒症 |
||||||
| 兔 |
1.肌病 | 2.骨硬化症 |
Hackel |
1968 | |||||
| 大鼠 |
Marks |
1973 |
Nakhooda |
1975 | |||||
| 牛 |
Greene |
1974 |
小鼠、地鼠 |
Bulter |
1970 | ||||
| Leipoid |
1970 |
小鼠 |
Butler |
1972 | |||||
| 3.骨肉瘤 |
Chick |
1970 | |||||||
| 狗 |
Thurman |
1973 |
Iwatsuka |
1974 | |||||
| 4.骨肿瘤 |
Herberg |
1977 | |||||||
| 灵长类 |
Pappagianis |
1973 |
Walkley |
1978 | |||||
| 小鼠 |
Franks |
1973 |
Wehner |
1972 | |||||
| 5.慢性骨髓炎 |
Yamada |
1969 | |||||||
| 兔 |
Andriole |
1973 |
Mittl |
1970 | |||||
| 6.多趾、并趾畸形 |
Coleman |
1978 | |||||||
| 小鼠 |
Johnson |
1971 |
灵长类 |
Howard |
1972 | ||||
| Gruneberg |
1964 |
1976 | |||||||
| 7.骨关节病 |
豚鼠 |
Munger |
1973 | ||||||
| 小鼠 |
Silberberg |
1962 |
狗 |
Kramer |
1980 | ||||
续表
| 猫 |
Johnson |
1973 |
Karlinsky |
1978 | |
| 兔 |
Roth |
1980 |
地鼠 |
Hayes |
1975 |
| Kramer |
1980 |
其他 |
Slauson |
1980 | |
| 猪 |
Lang |
1977 |
Slauson |
1980 | |
| 3.甲状腺功能减退 |
3.肺炎 | ||||
| 狗 |
Lombard |
1962 |
灵长类 |
Pirie |
1971 |
| 鸡 |
Cole |
1966 |
大鼠兔 |
Johnson |
1974 |
| 4.肥胖症 |
狗 |
Pinkerton |
1945 | ||
| 小鼠 |
Sinha |
1975 |
4.肺结核 | ||
| Eigher |
1976 |
灵长类 |
Good |
1968 | |
| 大鼠 |
Zucher |
1962 |
Moreland |
1970 | |
| Bray |
1971 |
5.哮喘 | |||
| 其他 |
Bray |
1977 |
狗 |
Patterson |
1974 |
| 5.垂体机能改变 |
6.肺萎缩 | ||||
| 小鼠 |
Baroni |
1972 |
马 |
Mahaffey |
1957 |
| Ficher |
1976 |
(六)神经系统 | |||
| Sinha |
1975 |
1.癫痫 | |||
| Hummel |
1964 |
小鼠 |
Ward |
1971 | |
| 狗 |
Willeberg |
1975 |
兔 |
Hohenboken |
1970 |
| Pollock |
1951 |
Sawin |
1955 | ||
| 6.甲状腺机能改变 |
灵长类 |
Riche |
1971 | ||
| 狗 |
Lombardi |
1962 |
鸡 |
Crawford |
1970 |
| 鸡 |
Cole |
1966 |
狗 |
Bielfelt |
1971 |
| Wick |
1974 |
Croft |
1968 | ||
| 7.睾丸女性化 |
Van der |
1968 | |||
| 小鼠 |
Kes |
1970 |
2.小脑病变 | ||
| 大鼠 |
Stanley |
1973 |
猫 |
Kilham |
1966 |
| (五)呼吸系统 |
狗 |
Corday |
1952 | ||
| 1.过敏性肺炎 |
小鼠 |
Sidman |
1965 | ||
| 兔 |
Parish |
1961 |
Yoon |
1972 | |
| Richerson |
1971 |
Rezai |
1972 | ||
| 豚鼠 |
Wilkie |
1973 |
3.衰老症 | ||
| 大鼠 |
Fink |
1970 |
鹿、猫、狗、小鼠 | ||
| 灵长类 |
Hensley |
1974 |
Dayan |
1971 | |
| 2.肺气肿 |
水貂、小鼠、牛 | ||||
| 牛 |
Dickinson |
1967 |
Hirano |
1971 | |
| 马 |
Gillespie |
1975 |
Okano |
1971 | |
| 大鼠 |
Palecek |
1971 |
Sung |
1971 | |
| Gross |
1965 |
狗 |
Koppang |
1974 | |
| 小鼠 |
Fisk |
1976 |
Patel |
1974 | |
续表
| 猫 |
Geen |
1974 |
地鼠 |
Shirai |
1967 |
| 4.脑积水 |
水貂 |
Henson |
1974 | ||
| 小鼠 |
Borit |
1972 |
马 |
Cochrane |
1973 |
| Raimondi |
1973 |
灵长类 |
Poskitt |
1973 | |
| Taraszewska |
1970 |
3.肾盂积水 | |||
| 5.白质营养不良症 |
小鼠 |
Wamer |
1971 | ||
| 小鼠 |
Buumann |
1968 |
大鼠 |
Cohen |
1970 |
| Bennett |
1971 |
Lozzio |
1972 | ||
| 5.肾皮质囊肿 | |||||
| 6.脑疝 |
兔 |
Fox |
1971 | ||
| 小鼠 |
Bennett |
1959 |
6.多囊肾 | ||
| 7.震颤症 |
地鼠 |
Gleiser |
1970 | ||
| 小鼠 |
Braverman |
1953 |
7.尿石症 | ||
| Lord |
1929 |
大鼠 |
Magnusson |
1971 | |
| (七)泌尿、生殖系统 |
猫 |
Jackson |
1968 | ||
| 1.原发性小球肾炎 |
8.肾盂肾炎 | ||||
| 大鼠 |
Van Relt |
1972 |
牛 |
Thorp |
1943 |
| 羊 |
Steblay |
1980 |
狗 |
Bloon |
1937 |
| Lerner |
1966 |
9.肾变性 | |||
| Angus |
1975 |
小鼠 |
West |
1965 | |
| 猫 |
Slauson |
1971 |
Hulse |
1965 | |
| 灵长类 |
Burkholder |
1970 |
10.雌雄间体 | ||
| Poskitt |
1974 |
狗 |
Stewart |
1972 | |
| 狗 |
Kurtz |
1972 |
猪 |
Bagnall |
1974 |
| 2.继发性肾小球肾炎 |
Miyake |
1973 | |||
| 小鼠 |
Meblors |
1971 |
Melander |
1971 | |
| Porter |
1971 |
11.妊娠毒血症 | |||
| Buchmeier |
1978 |
兔 |
Wardle |
1973 | |
| Cheville |
1978 |
Creene |
1938 | ||
| Lambert |
1968 |
豚鼠 |
Jay |
1963 | |
| Like |
1972 |
12.睾丸女性化 | |||
| Wehner |
1972 |
小鼠 |
Lund |
1970 | |
| Falconer |
1964 |
Ohno |
1974 | ||
| 大鼠 |
Valtin |
1977 |
大鼠 |
Stanley |
1973 |
续表
| 13.隐睾症 | Harvey | 1974 | |||
| 猪 | Mcphee | 1934 | 鹿 | Huetis | 1956 |
| (八)免疫系统 | 大鼠 | Werth | 1967 | ||
| 1.过敏性哮喘 | 小鼠 | Martinell | 1981 | ||
| 豚鼠，狗 | Patterson | 1974 | Edwards | 1975 | |
| 2.自体免疫性疾病 | Hutton | 1973 | |||
| 小鼠 | Howie | 1968 | Gruneberg | 1939 | |
| Peterson | 1972 | Stevens | 1958 | ||
| 狗 | Lewis | 1971 | Falconer | 1962 | |
| Hurvity | 1980 | Nash | 1964 | ||
| Palmer | 1980 | 兔 | Falconer | 1979 | |
| Dodds | 1978 | 2.白血病 | |||
| 大鼠 | Hajdu | 1969 | 鸡 | Pomeroy | 1973 |
| 3.免疫功能缺陷疾病 | Shifrine | 1973 | |||
| ①T细胞功能缺陷 | 小鼠 | Kufe | 1972 | ||
| 裸小鼠 | Flangan | 1936 | Mellors | 1969 | |
| Fogh | 1978 | Rowe | 1972 | ||
| 裸大鼠 | Festing | 1981 | Skipper | 1972 | |
| 裸豚鼠 | O'Donoghue | 1981 | Wolman | 1982 | |
| 牛 | Brwmmerstedt | 1978 | 大鼠 | Hoelzer | 1973 |
| ②B细胞功能缺陷 | Moloney | 1974 | |||
| 鸡 | Luster | 1977 | Richter | 1972 | |
| Benedict | 1978 | Rosenthal | 1972 | ||
| 马 | Banks | 1976 | 豚鼠 | Kaplow | 1979 |
| Perrymen | 1980 | 猫 | Olson | 1980 | |
| 牛 | Nansen | 1972 | Cotter | 1977 | |
| 小鼠 | Welles | 1981 | 3.卟啉病 | ||
| ③T和B淋巴细胞均缺陷 | 牛 | Kaneko | 1963 | ||
| 小鼠 | Erickson | 1981 | 猪 | Jrgensen | 1963 |
| Azar | 1980 | 4.出血性疾病 | |||
| Kincade | 1981 | 大鼠 | Tschopp | 1972 | |
| 马 | Mcguire | 1976 | 小鼠 | Novak | 1981 |
| ④其他 | 狗 | Dodds | 1981 | ||
| 小鼠 | Daguesney | 1972 | Raymond | 1979 | |
| Helniger | 1974 | Benson | 1976 | ||
| (九)血液病 | 其他 | Rvdes | 1981 | ||
| 1.红细胞异常和贫血 | Kociba | 1976 | |||
| 狗 | Tasker | 1969 | 豚鼠 | Bodds | 1977 |
| Searey | 1979 | 兔 | Rother | 1966 | |
| Lelchworth | 1977 | Benson | 1977 | ||
续表
| 猫 |
Cotter |
1978 |
大鼠 |
Leonard |
1971 | ||
| Kier |
1980 |
Smith |
1969 | ||||
| Coeen |
1977 |
狗 |
Rubin |
1974 | |||
| (十)皮肤病 |
Heywood |
1971 | |||||
| 1.红斑狼疮 |
3.糖尿病角膜、视网膜病变 | ||||||
| 狗 |
Lewis |
1973 |
小鼠 |
Huang |
1971 | ||
| 小鼠 |
Lambert |
1968 |
其他 |
Soret |
1973 | ||
| 2.埃一当二代综合征 |
4.无眼、小眼畸形 | ||||||
| 狗、水貂 |
Hegreberg |
1974 |
豚鼠 |
Komich |
1971 | ||
| 3.黑色素瘤 |
小鼠 |
Kimura |
1969 | ||||
| 小鼠 |
Lejeun |
1973 |
Konyukhov |
1969 | |||
| 4.白化病 |
5.视网膜疾病 | ||||||
| 地鼠 |
Pomereanfg |
1974 |
灵长类 |
Aaberg |
1970 | ||
| 牛 |
Greene |
1973 |
牛 |
Bistner |
1970 | ||
| 小鼠 |
Coleman |
1962 |
Leipold |
1968 | |||
| Pomeraurg |
1974 |
狗 |
Rubin |
1968 | |||
| 5.麻风病 |
小鼠 |
Caley |
1972 | ||||
| 猪 |
Schiavo |
1974 |
Blanks |
1974 | |||
| 大鼠 |
Kirchheimer |
1973 |
Keeler |
1970 | |||
| 狨 |
Convit |
1974 |
Nagy |
1972 | |||
| 6.皮脂腺缺乏 |
大鼠 |
Heron |
1974 | ||||
| 小鼠 |
Gates |
1965 |
Yates |
1974 | |||
| 7.鱼鳞症 |
猫 |
Rubin |
1969 | ||||
| 小鼠 |
Spearman |
1960 |
6.内耳、耳蜗变形 | ||||
| 8.遗传性稀毛症 |
Deol |
1958 | |||||
| 牛 |
Hutt |
1953 |
豚鼠 |
Ernstson |
1972 | ||
| 9.过敏性皮炎 |
7.遗传性耳聋 | ||||||
| 狗 |
Muller |
1967 |
Saunders |
1965 | |||
| 豚鼠 |
Rook |
1965 |
小鼠 |
Deol |
1968 | ||
| (十一)五官科疾病 |
猫 |
Calkins |
1956 | ||||
| 1.青光眼 |
Bergsma |
1971 | |||||
| 狗 |
Gelatt |
1981 |
West |
1973 | |||
| 大鼠 |
Young |
1974 |
8.老年性耳聋 | ||||
| 兔 |
Koler |
1963 |
Crowley |
1972 | |||
| Fox |
1971 |
(十二)肿瘤 | |||||
| 其他 |
Gelatt |
1977 |
1.肺肿瘤 |
||||
| 2.白内障 | 小鼠 |
Bloam | 1964 | ||||
| 小鼠 |
Brown |
1970 |
灵长类 | Schepers |
1971 | ||
| Hunter |
1974 |
牛 |
Senton |
1958 | |||
| Iwata |
1971 |
2.淋巴瘤 | |||||
| Pierro |
1970 |
牛 |
Schneider |
1970 | |||
| 羊、牛、猪、马 |
|||||||
续表
| Miller |
1974 | 10.黑色素瘤 |
|||||
| 鸡 |
Purchase |
1972 |
|||||
| 狗 |
Cohen |
1970 |
|||||
| 小鼠 |
Gardner |
1973 |
小鼠 |
Burger |
1973 | ||
| Schwarozmann |
1972 |
猪 |
Millkan |
1974 | |||
| 鹌鹑 |
Nishimura |
1970 |
马 |
Lerner |
1973 | ||
| 兔 |
Fox |
1970 |
裸小鼠 |
Albert |
1980 | ||
| Hinze |
1972 |
11.多发性骨髓瘤 |
|||||
| 灵长类 |
Hunt |
1973 |
马 |
Cornelius |
1959 | ||
| Kawakaml |
1975 |
牛 |
Pearce |
1955 | |||
| 3.骨肿瘤 | 猪 |
Englert | 1955 | ||||
| 小鼠 |
Franks |
1973 |
狗 |
Medway |
1967 | ||
| 4.非嗜铬性付神经节瘤 | 12.血管瘤 | ||||||
| 狗 |
Hayes |
1974 |
狗 |
Schwartzman |
1962 | ||
| 5.畸胎瘤 | 13.皮肤纤维瘤 | ||||||
| 小鼠、兔 |
Stevens |
1973 |
狗 |
Schwartzman |
1962 | ||
| Meier |
1970 |
14.子宫肿瘤 |
|||||
| 6.乳腺癌 | 小鼠 |
Dawson | 1974 | ||||
| 小鼠 |
Belyaev |
1972 |
15.睾丸肿瘤 |
||||
| Hehlmann |
1974 |
大鼠 |
Vanha-Perttula |
1970 | |||
| Hoston |
1972 |
16.前列腺瘤 |
|||||
| Lasfargues | 1974 |
兔 |
Wardle |
1973 | |||
| Matsuzawa |
1970 |
17.卵巢肿瘤 |
|||||
| Schlom |
1973 |
小鼠 |
McGowan |
1970 | |||
| 猫 |
Squartini |
1974 |
大鼠 |
Fitzgerald |
1974 | ||
| Stolfi |
1971 |
Mawclesley |
1974 | ||||
| 猫 |
Strandberg |
1974 |
19.胃肠腺癌 |
||||
| Hayden |
1971 |
大鼠 |
Basrur |
1971 | |||
| Misdorp |
1980 |
Randeria |
1979 | ||||
| 狗 |
Schneider |
1970 |
20.喉癌 |
||||
| 7.淋巴肉瘤 | 地鼠 |
Homburger | 1979 | ||||
| 猫 |
Hardy |
1971 |
21.宫颈癌 |
||||
| 8.肝胚细胞瘤、肝细胞肝癌 | 小鼠 | Rubio | 1977 | ||||
| 小鼠 |
Truusov |
1973 |
Forsberg |
1976 | |||
| 鱼 |
Ashley |
1973 |
22.垂体肿瘤 | ||||
| 大鼠 |
Newberne |
1973 |
大鼠 |
Ito |
1976 | ||
| 9.肾腺癌 |
23.甲状腺髓样癌 | ||||||
| 蛙 |
Granoff |
1973 |
大鼠 |
Boorman |
1976 | ||
| Mckinnel |
1972 |
24.支气管原癌支气管肺泡细胞癌 |
|||||
| Mohr |
1980 |
大鼠、小鼠 |
Prejean |
1973 |
| Nobel |
1978 |
灵长类 |
Caminitr |
1974 |
| 鸡、猫、牛 | Anon | 1973 | ||
| Hollander |
1971 |
|||
| Smith |
1973 |
|||
| Mackenzie |
1973 |