消痰散结方对裸鼠人胃癌血管生成的影响
消痰散结方;胃癌;血管生成;微血管密度;血管容积指数;三维超声,郑国静,石健,于有德,郑国静,通讯作者:,EffectofXiaotanSanjierecipeontheangiogenesisofnudemicewithhumangastricc
 |
| 第1页 |
参见附件(999KB，5页)。
郑国静, 石健, 临淄区人民医院肿瘤科 山东省淄博市 255400
于有德, 临淄区人民医院胸外科 山东省淄博市 255400
郑国静, 2005年第二军医大学临床医学博士, 主要从事中西医结合防治消化道肿瘤的基础与临床研究.
通讯作者: 郑国静, 255400, 山东省淄博市临淄区桓公路139号, 临淄区人民医院肿瘤科. zhengguojinglinzi@yahoo.com.cn电话: 0533-7162026 传真: 0533-7180469
收稿日期: 2006-12-10 接受日期: 2006-12-27
Effect of Xiaotan Sanjie recipe on the angiogenesis of nude mice with human gastric carcinoma
Guo-Jing Zheng, You-De Yu, Jian Shi
Guo-Jing Zheng, Jian Shi,Department of Oncology, People’s Hospital of Linzi District, Zibo 255400, Shandong Province, China
You-De Yu,Department of Thoracic Surgery, People’s Hospital of Linzi District, Zibo 255400, Shandong Province, China
Correspondence to:Guo-Jing Zheng, Department of Oncology, People’s Hospital of Linzi District, 139 Huangong Road, Linzi District, Zibo 255400, Shandong Province, China. zhengguojinglinzi@yahoo.com.cn
Received:2006-12-10 Accepted:2006-12-27
Abstract
AIM: To investigate the effect of Xiaotan Sanjie recipe (XSR) on the angiogenesis of nude mice with human gastric carcinoma.
METHODS: The model of nude mice with human gastric carcinoma was made, and then all the mice were randomly divided into group A, B and C, treated with normal saline, XSR (0.2 mL once a day, ig) and XSR (0.2 mL once a day, ig) plus 5-fluorouracil (0.2 mL, once a week), respectively, for 6 weeks. The experiment was terminated in the 11th week. All the mice were detected by the color Doppler, and the images were three-dimentionally rebuilt by TOMTEC imaging system to evaluate the vascularity volume index (Ⅵ). All the mice were sacrificed and the tumor tissues were collected for the observation of CD34 using Envision immunohistochemical staining. Finally, the microvessel density (MVD) was calculated.
RESULTS: In comparison with that in group A (2.14 ± 0.43 g), the tumor weight in group B (1.12 ± 0 ......
您现在查看是摘要介绍页，详见PDF附件(999KB，5页)。