部分脾动脉栓塞术治疗肝硬化脾功能亢进39例
脾功能亢进;脾栓塞术;栓塞面积;疗效;并发症,李璐,曾争,尹彪,蔺小红,万华,霍娜,徐京杭,徐小元,通讯作者:,Partialsplenicembolizationforlivercirrhosisaccompaniedbyhypersplenism
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李璐, 曾争, 尹彪, 蔺小红, 万华, 霍娜, 徐京杭, 徐小元, 北京大学第一医院感染疾病科 北京市 100034
国家自然科学基金资助项目, No. 30271182
国家“十五”攻关课题 No. 2001BA705B06
通讯作者: 徐小元, 100034, 北京市西城区西什库大街8号, 北京大学第一医院感染疾病科. yangpin@public3.bta.net.cn
电话: 010-66551122-2370
收稿日期: 2007-01-30 接受日期: 2007-03-06
Partial splenic embolization for liver cirrhosis accompanied by hypersplenism: an analysis of 39 cases
Lu Li, Zheng Zeng, Biao Yin, Xiao-Hong Lin, Hua Wan, Na Huo, Jing-Hang Xu, Xiao-Yuan Xu
Lu Li, Zheng Zeng, Biao Yin, Xiao-Hong Lin, Hua Wan, Na Huo, Jing-Hang Xu, Xiao-Yuan Xu,Department of Infectious Diseases, the Affiliated Hospital of Peking University, Beijing 100034, China
Supported byNational Natural Science Foundation of China, No. 30271182 and the National Key Foundation during the Tenth Five-Year Plan Period, No. 2001BA705B06
Correspondence to:Xiao-Yuan Xu, Department of Infectious Diseases, the Affiliated Hospital of Peking University, 77 Xishiku Street, Beijing 100034, China. yangpin@public3.bta.net.cn
Received:2007-01-30 Accepted:2007-03-06
Abstract
AIM: To evaluate the efficacy of partial splenic embolization (PSE) in the treatment of patients with liver cirrhosis accompanied by hypersplenism and investigate the complications associated with PSE.
METHODS: Thirty-seven cases of liver cirrhosis accompanied by hypersplenism who had received PSE (totally 39 times) were analyzed retrospectively. The observation time was from 0.1 to 60 months. The observation indexes included leukocyte count, hemoglobin, platelet count and side effects.
RESULTS: After PSE, leukocyte and platelet counts were higher than those before PSE (P < 0.05). No significant changes occurred in hemoglobin after PSE (except 15 months). Larger-area embolization produced a better efficacy than smaller-area one in short term, but not in long term. The side effects that happened most frequently were abdominal pain (94 ......
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