多层螺旋CT和血清肿瘤标志物对胃癌术前评估的价值

http://www.100md.com 2007年10月28日 严 超, 朱正纲, 燕 敏, 陈克敏, 陈 军, 刘炳亚, 尹浩然, 林言箴

闂佺ǹ绻戞繛濠囧极椤撶姵瀚氱€广儱绻掔粣锟�胃肿瘤;体层摄影术,多层螺旋CT;肿瘤标志物,严超,朱正纲,燕敏,陈军,刘炳亚,尹浩然,林言箴,陈克敏,严超,通讯作者:,Clinicalsignificanceofmulti-slicespiralCTandserumtumormarke

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     严超, 朱正纲, 燕敏, 陈军, 刘炳亚, 尹浩然, 林言箴, 上海交通大学医学院附属瑞金医院普外科 上海消化外科研究所 上海市 200025

    陈克敏, 上海交通大学医学院附属瑞金医院放射科 上海市 200025

    严超, 临床医学博士, 主治医师, 主要从事胃癌外科综合治疗的基础与临床研究.

    通讯作者: 朱正纲, 200025, 上海市, 上海交通大学医学院附属瑞金医院普外科、上海消化外科研究所. zzg1954@hotmail.com

    电话: 021-64370045-666051

    收稿日期: 2007-06-30 修回日期: 2007-09-29

    Clinical significance of multi-slice spiral CT and serum tumor markers in the preoperative assessment of gastric carcinoma

    Chao Yan, Zheng-Gang Zhu, Min Yan, Jun Chen, Bing-Ya Liu, Hao-Ran Yin, Yan-Zhen Lin,Department of General Surgery, Ruijin Hospital, Medical College of Shanghai Jiaotong University, Shanghai Institute of Digestive Surgery, Shanghai 200025, China

    Ke-Min Chen, Department of Radiology, Ruijin Hospital, Medical College of Shanghai Jiaotong University, Shanghai 200025, China

    Correspondence to: Zheng-Gang Zhu, Shanghai Institute of Digestive Surgery, Department of General Surgery, Ruijin Hospital, Medical College of Shanghai Jiaotong University, Shanghai 200025, China. zzg1954@hotmail.com

    Received: 2007-06-30 Revised: 2007-09-29

    Abstract

    AIM: To investigate the value of multi-slice spiral CT (MSCT) and serum tumor markers in the preoperative assessment of gastric carcinoma.

    METHODS: MSCT was performed preoperatively in 220 patients with gastric carcinoma confirmed by biopsy, and the results were compared with surgical pathological findings. In addition, preoperative serum tumor marker levels of CA125, CA19-9, CA72-4, CEA and AFP were measured, and the correlation between tumor marker levels and clinicopathological parameters of gastric carcinoma was analyzed.

    RESULTS: The overall accuracy of MSCT in preoperative T staging of gastric carcinoma was 78.64%. The overall accuracy of MSCT in preoperative N staging of gastric carcinoma was 74.09%. The diagnostic sensitivity, specificity and accuracy of MSCT for determining distant metastases of gastric carcinoma were 65 ......

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