病毒性肝炎后肝硬化发生的临床危险因素研究进展
肝硬化;危险因素;肝炎病毒;酒精;肝脂肪变性,叶华曦,张焜和,通讯作者:,Advancesinresearchofclinicalriskfactorsforthedevelopmentofcirrhosisduetoviralhepatitis
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叶华曦, 南昌大学第三附属医院消化内科 江西省南昌市 330008
张焜和, 南昌大学第一附属医院消化内科 江西省南昌市 330006
通讯作者: 张焜和, 330006, 江西省南昌市, 南昌大学第一附属医院消化内科. yfyzkh@sina.com
电话: 0791-8692507
收稿日期: 2007-08-21 修回日期: 2007-10-29
Advances in research of clinical risk factors for the development of cirrhosis due to viral hepatitis
Hua-Xi Ye, Kun-He Zhang
Hua-Xi Ye, Department of Gastroenterology, the Third Affiliated Hospital, Nanchang University, Nanchang 330008, Jiangxi Province, China
Kun-He Zhang, Department of Gastroenterology, the First Affiliated Hospital, Nanchang University, Nanchang 330006, Jiangxi Province, China
Correspondence to: Kun-He Zhang, Department of Gastroenterology, the First Affiliated Hospital, Nanchang University, Nanchang 330006, Jiangxi Province, China. yfyzkh@sina.com
Received: 2007-08-21 Revised: 2007-10-29
Abstract
Patients infected with hepatitis viruses may have different clinical outcomes, some of whom develop liver cirrhosis. Understanding the risk factors for liver cirrhosis is of importance in clinical practice. Recent studies have shown that the development of liver fibrosis and cirrhosis is correlated with the type of hepatitis virus and its genotype, clinical features of viral hepatitis, alcohol consumption, and liver steatosis. These risk factors may contribute independently or jointly to the development of cirrhosis due to viral hepatitis.
Key Words: Liver cirrhosis; Risk factor; Hepatitis virus; Alcohol; Steatosis
Ye HX, Zhang KH. Advances in research of clinical risk factors for the development of cirrhosis due to viral hepatitis. Shijie Huaren Xiaohua Zazhi 2007; 15(32): 3430-3434
摘要
目的: 肝炎病毒感染患者有着不同的临床转归, 其中一部分将发展为肝硬化. 了解肝硬化发生发展的临床危险因素对临床实践具有重要的指导意义. 近年来研究显示, 肝炎病毒类型及其基因型、病毒性肝炎的临床特点、饮酒、肝脂肪变性等临床因素与肝纤维化和肝硬化的发生发展密切相关, 这些因素可独立或共同促使病毒性肝炎后肝硬化的发生.
关键词: 肝硬化; 危险因素; 肝炎病毒; 酒精; 肝脂肪变性
叶华曦, 张焜和 ......
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