树突状细胞治疗HBeAg阴性慢性乙型肝炎患者的临床观察

http://www.100md.com 司方明, 娄海山, 郑鹏远, 熊灵军, 范毅凯, 李俊红, 白经修

鍏抽敭璇嶏細乙型肝炎病毒;慢性乙型肝炎;树突状细胞;免疫治疗,司方明,郑鹏远,熊灵军,范毅凯,白经修,娄海山,李俊红,通讯作者:,ClinicalobservationofchronichepatitisBpatientswithnegativeHBe

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     司方明, 郑鹏远, 熊灵军, 范毅凯, 白经修, 郑州大学第二附属医院消化科 河南省郑州市 450014

    娄海山, 李俊红, 河南省许昌市人民医院感染科 河南省许昌市 461000

    河南省卫生厅医学创新人才工程资助项目, No. 2004-45

    河南省科技厅科技攻关资助项目, No. 0324410006

    通讯作者: 郑鹏远, 450014, 河南省郑州市经八路2号, 郑州大学第二附属医院消化科. medp7123@yahoo.com

    电话: 0371-65261035

    收稿日期: 2007-08-06 修回日期: 2007-10-25

    Clinical observation of chronic hepatitis B patients with negative HBeAg following dendritic cell vaccine treatment

    Fang-Ming Si, Hai-Shan Lou, Peng-Yuan Zheng, Ling-Jun Xiong, Yi-Kai Fan, Jun-Hong Li, Jing-Xiu Bai

    Fang-Ming Si, Peng-Yuan Zheng, Ling-Jun Xiong, Yi-Kai Fan, Jing-Xiu Bai, Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China

    Hai-Shan Lou, Jun-Hong Li, Department of Infectious Diseases, Xuchang People’s Hospital, Xuchang 461000, Henan Province, China

    Supported by: the Medical Innovation Talent Program of Health Department of Henan Province, No. 2004-45 and the Key Item of Science and Technology Department of Henan Province, No. 0324410006

    Correspondence to: Peng-Yuan Zheng, Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, 2 Jingba Road, Zhengzhou 450014, Henan Province, China. medp7123@yahoo.com

    Received: 2007-08-06 Revised: 2007-10-25

    Abstract

    AIM: To investigate the efficacy of dendritic cell (DC) vaccines in chronic hepatitis B patients with negative HBeAg.

    METHODS: HBV antigen-loaded dendritic cells (DCs) were injected into patients subcutaneously ......

    http://www.100md.com/html/200712/1858/1666.htm

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