哈萨克族食管癌与CYP2E1基因多态性及烟酒嗜好的关系
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陈 波, 马彦清, 杨 磊, 李 锋, 王秀梅, 廖佩花, 何 玲, 秦江梅
细胞色素P4502E1;基因多态性;食管癌;哈萨克族,陈波,杨磊,李锋,王秀梅,廖佩花,何玲,秦江梅,马彦清,通讯作者:,RelationshipofCYP2E1genepolymorphismandtobaccoandalcoholcon
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陈波, 杨磊, 李锋, 王秀梅, 廖佩花, 何玲, 秦江梅, 新疆地方病与民族高发病省部共建重点实验室 石河子大学医学院预防医学系 新疆维吾尔自治区石河子市 832002
马彦清, 新疆伊犁州友谊医院胸外科 新疆伊宁市 835000
国家自然科学基金资助项目, No. 30660161
国家重点基础研究发展规划资助项目(973计划), No. 2005CCA 03700
石河子大学博士基金资助项目, No. RCZX2004-PB17
2006年教育部科学技术研究重点资助项目, No. 206167
通讯作者: 秦江梅, 832002, 新疆维吾尔自治区石河子市, 石河子大学医学院预防医学系. qinjiangmei@yahoo.com.cn
电话: 0993-2057153 传真: 0993-2057153
收稿日期: 2007-08-12 修回日期: 2007-12-17
Relationship of CYP2E1 gene polymorphism and tobacco and alcohol consumption with susceptibility to esophageal cancer in Kazakh
Bo Chen, Yan-Qing Ma, Lei Yang , Feng Li, Xiu-Mei Wang, Pei-Hua Liao, Ling He, Jiang-Mei Qin
Bo Chen, Lei Yang, Feng Li, Xiu-Mei Wang, Pei-Hua Liao, Ling He, Yan-Qing Ma, Jiang-Mei Qin, Key Laboratory of the Ministry of Education, Xinjiang Endemic and Ethnic Diseases, Department of Preventive Medicine, Shihezi Medical University, Shihezi 832002, Xinjiang Uygur Autonomous District, China
Yan-Qing Ma, Department of Thoracic Surgery, Friendship Hospital of Xinjiang Yili Canton, Yining 835000, China
Supported by: National Natural Science Foundation of China, No. 30660161; the Major State Basic Research Development Program of China (973 Program), No. 2005CCA03700; the Doctor’s Fund of Shihezi University, No. RCZX2004-PB17; and the Scientific and Technology Research Key Program of Ministry in Education, No. 206167
Correspondence to: Dr. Jiang-Mei Qin, Department of Preventive Medicine, Shihezi Medical University, Shihezi 832002, Xinjiang Uygur Autonomous District, China. qinjiangmei@yahoo.com.cn
Received: 2007-08-12 Revised: 2007-12-17
Abstract
AIM: To study the interaction between polymorphism in CYP2E1 genotype and tobacco and alcohol consumption and risk of developing esophageal cancer (EC) in Kazakh.
METHODS: A 1∶2 matched case–control study was conducted with 120 cases of EC in Kazakh and 240 population-based controls ......
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