陈永鹏 章廉 卢桥生 骆抗先 梁蔚芳 冯筱榕 中华实验和临床病毒学杂志 1999年第3期第13卷 论著

    【摘要】 目的 探讨TTV病毒在不明原因肝炎中的意义及其所致肝损害的临床特征。方法 套式聚合酶链反应检测血清TTV病毒DNA并对TTV病毒阳性病例进行临床分析。结果 病原不明肝炎中TTV病毒感染率为38.6%；均为散发病例，多见于青壮年，男女无差别；症状明显，黄疸常见，血清转氨酶中度升高；肝组织呈汇管区炎症；一般病例预后良好，但合并症易加重病情。结论 TTV病毒可以解释病原不明肝炎中的部分病因。

    An inquire into the infection of a new virus(TTV)

    CHEN Yongpeng, ZHANG Lian, LU Qiaosheng, et al.

    (Department of Infectious Diseases of Nanfang Hospital, The First Military Medical University, Guangzhou, 510515)

    【Abstract】 Objective The aim of this study is to find out the prevalence of TTV in the cryptogenic hepatitis and the clinical features of TTV infected patients.Methods TTV DNA in the serum was tested by nested PCR and the clinical data was analyzed.Results Infection rate of the TTV in cryptogenic hepatitis was 38.6%. It was a sporadic disease, and involved mainly the adults, with no sexual difference. The symptoms were notable, often with jaundice, but the level of transaminase were elevated moderately. Histology revealed the portal area inflammation. If accompanied with other disease, the illness would be exacerbated.Conclusion TTV would be accounted for part of the reason in patients with cryptogenic hepatitis. ......