抗菌和抑酸治疗十二指肠溃疡的差别
十二指肠溃疡;幽门螺杆菌;抗生素;奥美拉唑;雷尼替丁李尚勤,徐克成,左建生,孟宪镛.抗菌和抑酸治疗十二指肠溃疡的差别.新消化病学杂志，1995;3(4):204-206H2受体拮抗剂应用于临床以来，消化性溃疡的治疗取得了长足的进步，H+-K+ATP酶抑制剂奥美拉唑(omeprazole,Ome)的问世，更
1北京邮电医院消化科 北京市 1000322南通医学院消化中心
李尚勤，男，1952-01-29生，北京市人，汉族.1992年在南通医学院获医学硕士学位，消化内科主治医师，主要从事消化性溃疡治疗的研究，发表论文3篇
项目负责人:北京大木仓胡同41号
Tel:010-6061177-291
收稿日期:1995-10-24
The differences between anti-acid and bactericidal treatments in duodenal ulcer
Shang-Qin Li1, Ke-Cheng Xu2, Jian-Sheng Zuo2 and Xian-Yong Meng2
1Department of Gastroenterology, Beijing Post and Telecommunication Hospital, Beijing 100032 China
2Gastroenterology Center, Nantong Medical College, Nantong 226001 China
Abstract
AIMS To study the differences between the antibacterial therapy, losec(omeprazole) and ranitidine in the treatment of duodenal ulcer(DU).
METHODS The urease test, Helicobacter pylori scores histologically, the improvement of inflammation in the antrum and duodenum, and the electric microscopy study on the tissue around the ulcer were studied in 64 patients with DU before and after 4 weeks of treatment.
RESULTS In the clearance of Helicobacter pylori(for urease test positive rates 100%→9%, 88%→54%, 89%→89%) and the recovery of tissue pathology(for inflammation scores around the ulcer, 2.9±0.1→1.8±0.2, 2.6±0.2→2.6±0.3, 2.7±0.3→2.6±0.2) ......
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