血浆花生四烯酸代谢紊乱在大鼠急性胰腺炎 肝脏损害发病机理中的作用
胰腺炎,病理生理学;肝,病理学;急性病;花生四烯酸,血液;花生四稀酸,代谢,血浆花生四烯酸代谢紊乱在大鼠急性胰腺炎肝脏损害发病机理中的作用,项目负责人,Theroleofarachidonicacidmetabolitesinliverdamageinacuteexperimentalpancreatitisinrats,Abstract,AIM,METHODS,RESULTS
四川省卫生管理干部学院外科 四川省成都市 610041沈骥，男，1961-07-08生，江苏省泰兴市人，汉族.1983年南京铁道医学院毕业，医学硕士、外科副教授，世界胰腺学学会会员，主要从事有关胰腺疾病的研究，发表论文30篇，主编参编专著3部.
项目负责人 沈骥,四川省成都市汪家拐街16号.
Tel: 028-6632902-2451.收搞日期 1996-02-04 接受日期 1996-07-02
The role of arachidonic acid metabolites in liver damage in acute experimental pancreatitis in rats
Ji Shen, Hua Xiao, Zhong-Ping Wu, Yong_Hui Song and Ming Liu
Department of Surgery, Continuing Education College of Medical Scien ces, Chengdu 610041, Sichuan Province, China
Abstract
AIM To study the mechanism (plasma TXB2 and 6-Keto-PGF1α) of the liver damage in acute pancreatitis (AP).
METHODS In 140 rats (20 with sham operation as control group, 4 0 with 0.9% sodium chloride intrapancreatoductal injection induced acute oedema tous pancreatitis as AOP group and 80 with 5% sodium tauracholate intrapancreat oductal injection induced acute haemorrhagic panereatitis as AHP group), the pl asma thromoboxane (TXB2) and 6-keto-prostaglandin F1α (6-keto-PGF1α) levels and the pathohistology of liver were determined at 2- and 4-hour after induction of AP. ......
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