原发性肝细胞性肝癌社区危险度鉴别、评估和控制
*,国家自然科学基金资助项目，No.39470788；国家教委博士点基金资助项目，No.9602650.,项目负责人,SupportedbytheNationalNaturalSciencesFoundationofChina,No.39470788andSpecialResearchGrantsofDoctoralStationofEducationalM
上海医科大学预防医学研究所 上海市 200032俞顺章，男，1932-11-27生，上海市人，汉族. 1955年中国医科大学毕业，1959年上海第一医学院硕士，流行病学教授，发表论文100篇.
*国家自然科学基金资助项目，No.39470788；国家教委博士点基金资助项目，No.9602650.
项目负责人 俞顺章，200032，上海医科大学预防医学研究所.
Supported by the National Natural Sciences Foundation of China, No.39470788 and Special Research Grants of Doctoral Station of Educational Ministry of China, No.9602650.
Correspondence to Shun-Zhang Yu, Institute of Preventive Medicine, Shanghai Medical University, Shanghai 200032, China
Tel. +86·21·64041900 ext 2210, Fax. +86·21·64038931
E-mail: szyu@shmu. edu. cn
收稿日期 1998-07-29
Risk identification, assessment and control of primary hepatocellular cancer*
Shun-Zhang Yu and Chuan-Hui Dong
Institute of Preventive Medicine, Shanghai Medical University, Shanghai 200032, China
Abstract
AIM To identify the environmental risk factors of primary hepatocellular cancer (HCC) for assessment of community and individual risk as well as control of HCC.
METHODS In 1997, case-control study was conducted in Haimen, Jiangsu, and 64 HCC cases and 64 healthy controls matched with age, sex and residence were recruited. Univariate and multivariate logistic regression models were employed to screen the leading risk factors, estimate their relative risk and the weight for risk assessment of HCC were estimated. According to lot quality assurance sampling method, 13 villages in four counties were selected. HBsAg, aflatoxin-serum albumin adducts (AFT-HSA) and history of drinking pond-ditch water were investigated among 50 residents above 35 years old sampled from each village selected. Comprehensive risk assessment index of community and individual risk score were calculated based on the three risk factors mentioned above. The rank correlation was analyzed between HCC mortality rate of each village with the comprehensive index and individual risk score. ......
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