食管“Z”型支架术后局部粘膜血流量及通透性变化分析
食管狭窄治疗;食管血液供给;支架,国家自然科学基金资助，,No.39670341,项目负责人,SupportedbytheNationalNaturalScienceFoundationofChina,No.39670341,,Correspondenceto,Studyonchangesofmucosalbloodflowandpermeabili
中国人民解放军第二军医大学长海医院消化内科 上海市 200433宛新建，男，1968-12-02生，安徽省庐江县人，汉族. 1991年毕业于安徽医科大学医学系，1996年第二军医大学消化内科学硕士，1999年第二军医大学消化内科学博士，现为第二军医大学长海医院消化内科主治医师，主要从事消化系疾病介入诊疗研究.
国家自然科学基金资助，No.39670341
项目负责人 李兆申，200433，上海市长海路174号，中国人民解放军第二军医大学长海医院消化内科.
Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
Supported by the National Natural Science Foundation of China, No.39670341
Correspondence to Zhao-Shen Li, Department of Gastroenterology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China
Tel. +86-21-25070585
收稿日期 1999-10-19 接收日期 1999-11-15
Study on changes of mucosal blood flow and permeability after esophageal “Z” stenting
Xin-Jian Wan, Zhao-Shen Li, Guo-Ming Xu, Wen-Wang, Xian-Bao Zhan and Jing Liu
Abstract
AIM To study the changes of mucosal blood flow and permeability after esophageal “Z” stenting.
METHODS Twelve adult healthy dogs were divided into two groups, and the esophageal stent was placed respectively. Mucosal blood flow was measured with Dopplar blood flow meter, and compared with normal esophageal mucosa. Two hours after stenting PEG400 was perfused into the esophagus continuously under constant pressure in the first group for two hours. Equal weight of stenting and adjacent normal tissue were taken out, then homogenated and centrifuged. The amount of PEG400 in the supernatant was measured by gas liquid chromatography. Twenty-four hours after stenting, the same test was carried out in the second group. The mucosal structure was observed under electromicroscope 2 and 24 hours after stenting. ......
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