不同载体及靶基因对乙型肝炎病毒DNA疫苗免疫效果的影响
乙型肝炎病毒;基因免疫;乙型肝炎疫苗;细胞免疫;体液免疫,国家自然科学基金资助项目,,No.39770665,项目负责人,SupportedbytheNationalNaturalScienceFoundationofChina,No.39770665,Correspondenceto,EffectsofDNAvector
中国人民解放军第四军医大学唐都医院传染病科 陕西省西安市 710038王全楚,男,1966-12-11生,湖北省云梦县人,汉族,1990年第一军医大学本科毕业,1997年第四军医大学硕士研究生,主治医师,主要从事肝病的基础及临床研究,已发表论文30篇.
国家自然科学基金资助项目,No.39770665
项目负责人 王全楚,710038,陕西省西安市新寺路1号,中国人民解放军第四军医大学唐都医院传染病科.
Supported by the National Natural Science Foundation of China, No.39770665
Correspondence to Quan-Chu Wang, Department of Infectious Diseases, Tangdu Hospital, the Fourth Military
Medical University, 1 Xinsilu, Xi'an 710038, Shaanxi Province, China
Tel. 0086-29-3577595
Email. didthx@fmmu.edu.cn
收稿日期 1999-12-22 接收日期 2000-01-13
Effects of DNA vector constructs and different genes on the induction of immune
responses by HBV DNA-based vaccine
Quan-Chu Wang, Yong-Xing Zhou, Zhi-Qiang Yao and Zhi-Hua Feng
Department of Infectious Diseases, Tangdu Hospital, the Fourth Military Medical University, Xi'an 710038, Shaanxi Province, China
Abstract
AIM To study the effects of DNA vector constructs and different target genes on the efficiency of induction of immune responses to the HBV surface antigen (HBsAg) and HBV core antigen (HBcAg) in mice by DNA immunization. ......
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