地高辛素标记探针原位杂交技术检测肝硬变组织中TIMPs mRNA
肝硬化,病理学;金属蛋白酶1组织抑制剂,代谢;金属蛋白酶2组织抑制剂,代谢;RNA，信使,代谢;原位杂交;地高辛,地高辛素标记探针原位杂交技术检测肝硬变组织中TIMPsmRNA,本课题系中国博士后科学基金资助项目，中博基[,1999]10号.,项目负责人,Correspondenceto,DetectionofTIMP
中国人民解放军第四军医大学唐都医院传染病科 陕西省西安市 710038谢玉梅，女，1962-09-02生，吉林省长春市人，汉族. 1987年西安第四军医大学毕业，传染病科主治医师，讲师，硕士. 主要从事肝纤维化发病机制及中药治疗的研究，发表论文8篇(Tel. 0086-29-2235616).
本课题系中国博士后科学基金资助项目，中博基[1999]10号.
项目负责人 聂青和, 710038, 陕西省西安市，中国人民解放军第四军医大学唐都医院传染病科.
Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi＇an 710038, Shaanxi Province, China
Correspondence to Qing-He Nie, Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi＇an 710038, Shaanxi Province, China
Tel. 0086-29-3577595
Email. huanj@ fmmu.edu.cn
Received 2000-11-15 Accepted 2000-11-16
Detection of TIMP-1 and TIMP-2 RNA expressions in cirrhotic liver tissue using digoxigenin labelled probe by in situ hybridization
Yu-Mei Xie, Qing-He Nie, Yong-Xing Zhou, Yong-Qian Cheng and Wen-Zhen Kang
Abstract
AIM To investigate the distribution of tissue inhibitors of metalloproteinase-1 and -2 (TIMP-1 and TIMP-2) in liver cirrhosis tissue and its relationship with the function of TIMP-1 and TIMP-2 in pathogenesis of liver cirrhosis. ......
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