王凤君,赵云,汪仕良,王裴,中国人民解放军第三军医大学西南医院烧伤研究所 重庆市400038

    王凤君，男，1963-09-18生，四川省名山县人，汉族.1993年获第三军医大学医学硕士，1999年获第三军医大学医学博士，主要从事烧伤后肠黏膜损伤修复及肠道营养的研究.

    项目负责人 王凤君，400038，重庆市沙坪坝区高滩岩，中国人民解放军第三军医大学西南医院烧伤研究所. wangfj@mail.tmmu.com.cn

    电话:023-65317058 传真:023-65460398

    收稿日期 2002-07-16 接受日期 2002-08-03

    Effects of nutrition route on proliferation of intestinal epithelial cells in severe burn injury

    Feng-Jun Wang,Yun Zhao, Shi-Liang Wang, Pei Wang

    Feng-Jun Wang, Yun Zhao, Shi-Liang Wang, Pei Wang,Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing 400038, China

    Correspondence to:Dr. Feng-Jun Wang, Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. wangfj@mail.tmmu.com.cn

    Received 2002-07-16 Accepted 2002-08-03

    AbstractAIM:To investigate the effects of nutrition route on the proliferation of intestinal epithelial cells in severe burn injury.

    Methods:Rats inflicted with 30 %TBSA Ⅲ dgree burns were randomly divided into enteric feeding group (EF) and intravenous parenteral nutrition group (PN). To each animal of both groups, equal volume of nutritional support fluid containing predetermined amount of calories and nitrogen was supplied at 2 hr postburn (PBH). Protein content, thymidine kinase activity, proliferative index and PCNA expression in the intestinal mucosa were analyzed at 0, 6, 12, 24, 48, and 72 PBH respectively. ......