丁酸钠对结肠癌细胞株HT-29组织蛋白酶D表达水平的影响
李曦,罗和生,李凡,项目负责人,:,EffectofsodiumbutyrateontheexpressionofcathepsinsD,Correspondenceto:,Abstract,摘要,目的,方法,结果,结论,0,引言,1材料和方法,1.1材料,1.2方法,统计学处理,2结果,3讨论,4参考文献
李曦, 罗和生, 李凡, 武汉大学人民医院消化内科 湖北省武汉市 430060李曦, 男, 1977-12-21生, 湖北省宜昌人, 武汉大学人民医院消化内科医学博士.
项目负责人: 罗和生, 430060, 湖北省武汉市, 武汉大学人民医院消化内科. luotang@public.wh.hb.cn
电话: 027-88041911-2243
收稿日期: 2003-3-14 接受日期: 2003-03-25
Effect of sodium butyrate on the expression of cathepsins D
Xi Li, He-Sheng Luo, Fan Li
Xi Li, He-Sheng Luo, Fan Li, Department of Gastroenterology, Renmin Hospital, Wuhan University, Wuhan 430060, Hubei Province, China
Correspondence to: He-Sheng Luo, Department of Gastroenterology, Renmin Hospital, Wuhan University, Wuhan 430060, Hubei Province,China. luotang@public.wh.hb.cn
Received: 2003-03-14 Accepted: 2003-03-25
AbstractAIM: To detect the effect of sodium butyrate on the expression of cathepsins D(Cath-D) in HT-29 colon carcinoma cell.
METHODS: MTT assay, light microscopy and immunocytochemistry were used to observe the growth, apoptosis and expression of Cath-D in HT-29 cell line after treated by sodium butyrate
RESULTS: Sodium butyrate inhibited the growth of HT-29 cell lines, induced apoptosis and increased the expression of Cath-D in HT-29 cell line. ......
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