HLA-II类基因与慢性乙型肝炎重型化的相关性
蒋业贵,王宇明,项目负责人,:,AssociationbetweenHLAclassⅡgenesandseverityofchronichepatitisB,Correspondenceto:,Abstract,摘要,目的,方法,结果,结论,0,引言,1,材料和方法,1.1材料,1.2,统计学处理,2,结果,2.1HLA-DRB1等位基因检测
蒋业贵,王宇明,中国人民解放军第三军医大学西南医院全军感染病研究所 重庆市 400038蒋业贵,男, 1966-12-20生,安徽巢湖市人,汉族, 2002年获第三军医大学内科学博士学位,主治医师, 讲师.主要从事肝炎、肝硬化和消化系肿瘤的研究,发表论文30篇.
项目负责人:蒋业贵,400038, 重庆市,中国人民解放军第三军医大学西南医院全军感染病研究所. jiangyegui@yahoo.com.cn
电话:023-68754141
收稿日期:2003-03-08 接受日期:2003-04-05
Associationbetween HLA classⅡgenes and severity of chronic hepatitis B
Ye-GuiJiang, Yu-Ming Wang
Ye-Gui Jiang, Yu-Ming Wang, Institute of Infectious Diseases. SouthwestHospital, Third Military Medical University, Chongqing 400038, China
Correspondence to: Ye-Gui Jiang, Institute of InfectiousDiseases. Southwest Hospital, Third Military Medical University, Chongqing400038, China. jiangyegui@yahoo.com.cn
Received: 2003-03-08 Accepted:2003-04-05
AbstractAIM: To investigate the association between the polymorphism of HLA-DRB1, -DQA1 and -DQB1alleles and severity of chronic hepatitis B.
METHODS: HLA-DRB1, -DQA1 and -DQB1 alleles in 54 patients withchronic hepatitis B and 32 patients with chronic severe hepatitis B wereanalyzed by using polymerase chain reaction/sequence specific primer (PCR/SSP)technique. ......
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