【摘要】 目的 探讨膀胱移行细胞癌微血管密度与其临床病理的关系。方法 采用免疫组化S-P法，对68例膀胱癌组织标本血管内皮细胞行CD34染色，然后测定微血管密度(MVD)。结果 MVD与患者性别、肿瘤生长部位、大小无明显相关;不同病理组织学级别间MVD差异有显著性(P<0.05)，病理级别越高，MVD越大;浸润性癌与浅表性癌相比，MVD差异有非常显著性(P<0.01);有淋巴结转移者MVD显著高于无淋巴结转移者(P<0.01)。结论 膀胱移行细胞癌MVD与病理分级、临床分期及淋巴结转移关系密切，可作为一项有意义的预后指标。

    关键词 膀胱肿瘤 微血管密度

    Correlation between microvessel density and clinical

    pathological behaviour in transitional cell carcinoma of bladder

    Meng Qingze，Liu Dehai，Zhao Shouyuan，et al.

    Department of Urology，the153th Hospital of PLA，Zhengzhou450042.

    【Abstract】 Objective To study the correlation between microvessel density(MVD)and clinical pathological behaviour in transitional cell carcinoma(TCC)of bladder.Methods MVD were highlighted for CD34by means of imˉmunohistostaining the endothelial cells in68cases TCC.Results The MVD was statistically different in different grade of TCC(P<0.05) ......