【摘要】 目的 探讨HBV慢性感染者的主要死亡原因。方法 1992年在对90236例的人群进行HBV感染状况调查时检出HBsAg(+)者14338例，建立前瞻性研究队列。每年随访队列成员的生命状况，分析HBsAg(+)人群的主要死因，并以HBsAg(-)人群为对照。结果 HBsAg(+)人群的死亡率为1482.35/10万人年，死亡密度是对照组的3.42倍，肝癌是HBsAg(+)组的首位死因，占全部死亡的52.28%，与对照组相比，相对危险度=15.63，归因危险度百分比=93.60%。结论 感染HBV可促使肝癌发病提前。

    关键词 HBsAg(+) 死因 前瞻性研究

    A prospective study on causes of death of14338HBsAg(+)individuals

    Wang Lanping，Yu Xinsen，Qin Jian，et al.

    Haimen City Department of Health，Jiangsu226100.

    【Abstract】 Objective To investigate main cause of death of individuals with chronic HBV infection.Methˉods A prospective cohort was set up containing14338HBsAg(+)individuals，who were identified by screening for HBV infection within a population of90236people in1992.Survival analysis on the cohort was conducted each year and main cause of death examined.A group of HBsAg(-)individuals was set up for control.Results Mortality rate of HBsAg(+)group is1482.35per100 ......