【摘要】 目的 探讨神经肽Y(NPY)在原发性高血压发病中的作用。方法 采用放免分析法测定116例原发性高血压患者及26例健康对照组血浆NPY浓度。结果 对照组和原发性高血压1、2、3级组血浆NPY浓度分别为(4.96±0.28)Ln-μg/L、(5.20±0.39)Ln-μg/L、(5.40±0.26)Ln-μg/L、(5.71±0.18)Ln-μg/L，原发性高血压患者各组神经肽Y浓度均显著高于对照组(P均<0.05)，相关分析显示神经肽Y浓度与SBP、DBP均呈显著正相关(R分别为0.354、0.300，P<0.01)。结论 神经肽在原发性高血压发病中起重要作用。

    关键词 原发性高血压 神经肽Y

    Clinical significance of plasma neuropeptide Y released in patients with essential hypertension

    Li Junxiang，Fang Zhongliang

    Department of Cardiology，The Second Hospital of Yueyang City，Hunan414000.

    【Abstract】 Objective To investigate the effect of plasma neuropeptide Y(NPY)in patients with essential hypertension.Methods Plasma NPY levels in116patients with essential hypertension and26controls were meaˉsured by RIA.Results The plasma NPY levels in the control group and essential hypertension grade1 ......