【摘要】 目的 研究癌症患者对联合应用卡莫氟(化学名:1-乙胺基甲酰-5氟-2，4-嘧啶二酮)和放射治疗的耐受性，观察毒副反应。方法 将2001年10月～2002年12月间行术后放疗的85例乳腺癌患者分成A、B两组，所有患者均放疗8周。A组(45例)患者在放疗期间加服卡莫氟，B组(40例)患者行单纯放疗。观察毒副反应，对两组之间毒副反应进行评价和比较。结果 毒副反应主要表现为白细胞下降，两组之间毒副反应的差异无显著性(P>0.05)。结论 放疗加卡莫氟联合治疗的耐受性较好。在同步化放疗方案中卡莫氟的推荐剂量为600mg/天。

    关键词 乳腺肿瘤/治疗 综合疗法/放射治疗 卡莫氟/投药和剂量 副作用

    A clinical study of radiation therapy combining with carmofur used in postoperative mastocarcinomatous patients

    Zhang Zhisheng，Wang Jinke，Qian Tonghao

    Department of Oncology，The First Hospital Affliated to Zhangjiakou Medical College，Hebei075000.

    【Abstract】 Objective To evaluate the tolerance of postoperative mastocarcinomatous patients treated with raˉdiotherapy combining with carmofur.Methods Eighty-five postoperative mastocarcinomatous patients treated with radiotherapy were randomized into two groups.All patients were treated with radiotherapy for eight weeks.Patients in group A were treated with carmofur for eight weeks during radiotherapy.Patients in group B were treated with radioˉtherapy only.Having observed the toxic and side effects of all patients ......