【摘要】 目的 探讨肝动脉化疗栓塞(TACE)联合门静脉化疗(PVC)对肝癌合并门静脉癌栓的疗效和安全性。方法 总结2000年1月～2001年12月收治的无手术指征的肝癌合并门静脉癌栓46例。其中，TACE+PVC治疗16例(A组)，单纯TACE治疗30例(B组)作为对照。结果 A组和B组治疗后1、2年生存率分别为75.0%、36.7%和43.8%、10.0%，差异具有显著性(P<0.05和P<0.01)，而两组半年生存率及肝功能衰竭、上消化道出血的发生率无明显差异。结论 TACE+PVC治疗肝癌合并门静脉癌栓疗效优于单纯TACE，而且是安全可行的。

    关键词 肝肿瘤 癌 门静脉 癌栓 化疗

    Combined transcatheter arterial chemoembolization and portal vein chemotherapy

    in the treatment of primary liver cancer with portal vein tumor thrombus

    Tong ying，Yang Jiamei，Xu Feng，et al.

    The Third affiliated Hospital of the Second Military medical University，Shanghai200438

    【Abstract】 Objective To explore the therapeutic effect and safety of combined transcatheter arterial chemoembolization(TACE)and portal vein chemotherapy(PVC)for primary liver cancer(PLC)with portal vein tuˉmor thrombus(PVTT).Methods From January2000to December2001，46patients with unrcsectable PLC and PVTT were hospitalized.16cases(group A)of them were treated with TACE+PVC and the other30cases(group B)were treated with TACE only as control.Results The1- ......