【摘要】 目的 探讨降钙素基因相关肽(CGRP)和内皮素-1(ET-1)在电针抗心肌缺血中的保护作用。方法 选用异丙肾上腺素盐酸盐复制大鼠急性心肌缺血模型，检测电针心经“神门”-“通里”段经脉主干前后血浆CGRP和ET-1含量的变化。结果 电针后，血浆CGRP含量上升(P<0.01)，ET-1含量下降(P<0.05)，HRV的TV值减小，LF/HF比值下降速率减慢。结论 交感神经系统参与电针对心肌缺血性损伤的保护作用，CGRP是抗心肌缺血的主要介导物质之一。

    关键词 电针 心肌缺血 降钙素基因相关肽 内皮素-1

    Effects of electroacupuncture the heart meridian on contents of CGRP and

    ET-1in plasma in acute myocardial ischemia rats

    Wang Keming，Zhou Yiping，Wang Yuelan，et al.

    Research Centre on the Correlation between Channels and Viscera，Anhui College of Traditional Chinese Medicine，Hefei230038.

    【Abstract】 Objective To explore the protective role of CGRP and ET-1on electroacupuncture(EA)the heart meridian resisting the acute myocardial ischemia in rats.Methods Acute myocardial ischemia was modelled by high-dose isoproterenol hydrochloride(ISO)100mg/kg weight following ip.administration in rats.The content changes of CGRP and ET-1in plasma were observed before and after EA the“Shen-men”-“Tong-li”section of heart meridian.Results After EA ......