【摘要】 目的 了解大面积烧伤患者中心静脉导管细菌培养阳性率、细菌菌谱及药敏情况。方法 对1998年1月～2002年12月大面积烧伤患者中心静脉导管细菌培养进行回顾性分析。结果 培养216次，导管尖端培养阳性39次，阳性率为18.06%。革兰阳性菌14株，占36.90%;革兰阴性菌25株，占63.10%。药敏结果提示革兰阴性菌耐药率极高。结论 静脉导管感染是大面积烧伤治疗过程中的重要并发症，临床应以预防为主，革兰阳性菌对万石霉素、复方新诺明敏感性高，对革兰阴性菌效果稍好的抗生素是亚胺培南。

    关键词 烧伤 中心静脉导管 培养

    Analysis of positive catheter culture results in burn patients

    Yu Youxin，Fang Linsen，Hu Delin，et al.

    The First Affiliated Hospital，Anhui Medical University，Hefei230022.

    【Abstract】 Objective To study the incidence，bacteria spectrum and drug sensitivity of catheter-associated infection in extensive burn patients.Methods Retrospective study was made in extensive burn patients between Janˉuary1998and December2002.Results Among216central venous catheters，39strains of bacteria were cultivated，the positive incidence was18.06%.14germ-positive bacteria(36.90%);25germ-negative bacteria(63.10%).The drug resistance of germ-positive bacteria was obviously high.Conclusion Catheter-associated infection is the important complication in extensive burn patients.The best management is prevention.Germ-positive bacteria has high susceptibility to vancomycin and trimethoprim-sulfamethoxazole.Imipenem is the antibiotic that has slightly susˉceptibility to germ-negative bacteria. ......