【摘要】 目的 观察鼻内镜手术中，硝普钠复合艾司洛尔与单纯硝普钠控制性降压的比较。 方法 40例ASAⅠ～Ⅱ级进行功能性鼻内镜手术的病人被随机分成两组，每组20例。Ⅰ组病人接受硝普钠和艾司络尔进行控制性降压，Ⅱ组只接受硝普钠进行控制性降压。麻醉诱导用咪唑安定、芬太尼、异丙酚、万可松，用1%～2%异氟醚+50%N 2 O维持。两组病人术中平均动脉压保持在60～65mmHg之间，Ⅰ组病人通过调整艾司络尔用量将心率维持在80～90次/min。根据Fromme术野质量评分表在手术开始后5、15、30、45min由同一术者进行术野质量评分。 结果 Ⅰ组病人的术野质量评分明显低于Ⅱ组，其手术持续时间也少于Ⅱ组。 结论 单纯应用硝普钠轻度控制性降压并不能改善鼻内镜手术术野质量、缩短手术时间，硝普钠复合艾司络尔是较理想的降压方法。

    关键词 鼻内镜手术 硝普钠 术野质量 艾司洛尔

    Comparative study of controlled hypotension induced by sodium nitroprussion and esmolol or sodium nitroprussion only in functional endoscopic sinus surgery

    Pei Chunming，Luo Hengmao，Zhang Bingxi

    2002Master's Degree Candidate，Capital University of Medical Science，Beijing100540.

    【Abstract】 Objective To evaluate the effect of controlled hypotension by sodium nitroprussion and esmolol or sodium nitroprussion only in functional endoscopic sinus surgery(FESS).Methods Forty ASAⅠ-Ⅱpatients un-dergoing FESS were randomly divided into two groups:groupⅠreceived sodium nitroprussion and esmolol(n=20);groupⅡreceived sodium nitroprussion only(n=20).Anesthesia was induced with midazolam0.05mg/kg ......