【摘要】 目的 评价对患先天性鼻泪管阻塞的1岁内婴儿施行泪道探通术联合泪道内灌注氧氟沙星眼膏的临床效果。方法 因持续性泪溢、泪道冲洗不通，经泪囊区局部按摩无效而被确诊为先天性鼻泪管阻塞的1岁内婴儿60例(67眼)，在局麻下施行泪道探通术，并注入泪道以甲基纤维素为赋形剂的氧氟沙星眼膏，术后点滴氧氟沙星眼水1周。分别于术后第3天、第7天进行泪道冲洗，随访3个月，观察其临床症状的改善情况。结果 所有60例(67眼，100%)通过1～3次的治疗均获临床治愈。其中，1次治愈64眼，治愈率95.5%(64/67);2例(2眼)在首次术后第3天因冲洗泪道不通而再次手术后获治愈(3%:2/67);1例(1眼)则连续进行了3次手术方获治愈(1.5%:1/67)。无1例造成假道，唯一常见的并发症是在9例(10眼，14.9%)术后鼻腔分泌物中见少许血染。结论 对不满1岁的婴儿在局麻下施行鼻泪管探通术联合氧氟沙星眼膏灌注治疗其先天性鼻泪管阻塞是十分安全、简捷而有效的方法。

    Liu Chunmin，Yin Hong，Wang Yanjun

    Shenzhen Ophthalmic Centre，Medical College of Jinan University，Shenzhen51800.

    【Abstract】 Objective To assess the results of lacrimal duct probing followed by irrigation with ofloxacin based on methylcellulose in infants under1years old with epiphora，due to congenital nasclacrimal duct obstruction(CNLDO).Methods Following the failure of regular lacrimal sac massage，60infants(67eyes)under1years old with persistent epiphora and impeded lacrimal drainage systemwere performed lacrimal duct probing followed by irrigaˉtion with ofloxacin based on methylcellulose under topic anesthesia.Lacrimal duct rinsing was performed on the3rd and7th day.The percentage of eyes that showed complete resolution of symptoms3months after the final probing was calculated.Results All of the67lacrimal systems(100%)had complete resolution of symptoms and unimpeded lacrimal drainage systems after the probe1-3times.The cure rate was95.5%after the first probe ......