【摘要】 目的 分析鼻咽癌迟发性放射性脑病的诊断和治疗方法。方法 30例鼻咽癌放疗后迟发性放射性脑病患者行CT检查，其中10例行MRI检查，2例行正电子发射断层显像(Positron Emission Computed Tomography，PET)检查。结果和结论 (1)CT对鼻咽癌迟发性放射性脑病的诊断有一定价值，但MRI对后颅窝和脑干病变的显示优于CT;(2)迟发性放射性脑病可能是放疗致脑组织血管损伤后引起免疫改变的结果;(3)18-氟代脱氧葡萄糖( 18F-FDG)-PET是诊断迟发性放射性脑病的有效的影像学检查方法;(4)本组患者经应用激素、甘露醇、多种维生素等治疗，均取得不同程度的改善。对鼻咽癌放疗后迟发性放射性脑病应以预防为主并积极尽快治疗。

    关键词 鼻咽癌 迟发性放射性脑病 诊断 治疗

    Late radiation encephalopathy after radiotherapy for nasopharyngeal cacinoma

    Bu Junguo，Xiao Mingxing，Chen Xianglong，et al.

    Radiotherapy Department of Oncology Center，

    Zhujiang Hospital， First Military Medical Univercity，Guangzhou510282.

    【Abstract】 Objective To evaluate the method for diagnosis and treatment oflate radiation encephalopathy of nasopharyngeal cacinoma(NPC).Methods 30patients of late radiation encephalopathy with NPC due to radiotheraˉpy were examined with CT.Among whom10were also examined with MRI.2were also examined with PET.Results and Conclusions (1)MRI is better than CT to show the lesion of cerebellar fossa and brain stem.(2)Late radiation encephalopathy may be the result of immunal response to the damage of brain tissue and blood vessel after radiotherapy(3) 18 F-FDG-PET is a effective screenage examimation to diagnosis late radiation encephalopathy.(4)To some degree ......