【摘要】 目的 为评价早期干预对改善新生儿缺氧缺血性脑病(HIE)患儿智力发育的效果。 方法 82例HIE患儿按轻、中、重随机分干预组和对照组。干预组从新生儿期开始接受为期36个月干预治疗，所有病例均于出生后每隔3～6个月进行智能发育测查。 结果 干预组1岁、2岁、3岁时智力发育指数(MDI)和运动发育指数(PDI)比对照组高10～14分，且差异有显著性(P<0.01)，干预组康复率为95.1%，而对照组仅为80.5%。 结论 早期干预可促进HIE患儿智力发育，有效地防治所致的后遗症。

    关键词 新生儿 缺氧缺血性脑病 早期干预 智力

    The effects of the early intervention on prognosis of neonates with hypoxic ischemic encephalopathy

    Xia Ronghua，Deng Xianghong，Li Zhenhua，et al.

    Department of Pediatrics，Zhongshan City People's Hospital，Guangdong528403.

    【Abstract】 Objective To evaluate the effects of early intervention on improving the intellectual development of infants with hypoxic ischemic encephalopathy(HIE).Methods 82cases were collected to be randomly assigned to early intervention group and conventional care group.The treatment of early intervention was used to the intervention group for36months after birth.Just from the beginning of the birth ......