【摘要】 目的 评价经肝动脉化疗性栓塞(TACE)治疗直径10cm以上的巨块型肝癌的效果。 方法 对近5年来经肝动脉化疗性栓塞治疗的131例原发性巨块型肝癌进行回顾分析。 结果 TACE后30～45天复查，肿瘤体积明显缩小6.5%～57.3%，平均34.7%，其中瘤体体积缩小>50%者12例(9.2%)。AFP显著降低8.7%～45.1%，平均38.8%，无明显的化疗毒性反应。1、2、3年生存率分别为54.2%、23.7%、16.5%。 结论 经肝动脉TACE治疗巨块型肝癌安全、有效，可大大提高患者的生存率。

    关键词 肝细胞癌 化学治疗 栓塞 介入放射学

    Transcatheter arterial chemoembolization in treatment of massive hepatocellular carcinoma

    Qiu Yong，Chen Huadong，Wang Hao

    Department of Intervention and Radiology，Gaozhou People's Hospital，Gaozhou525200.

    【Abstract】 Objective To evaluate the effect of transcatheter arterial chemoembolization(TACE)on progno-sis of patients with massive hepatocellular carcinoma(>10cm).Methods 131cases of massive hepatocellular carci-noma were treated with chemoembolization.Their effectives were analyzed respectively.Results After30days to be followed up for45days.The tumor treated with TACE size shrinked obviously with the percentage of6.5%～57.3%(mean34.7%).The volume of tumor reduced more50%in12patients(9.2%)and AFP decreased significantly with the percentage of8.7%～45.1%(mean38.8%).No marked side effects of chemotherapeutic agent-induced were observed after TACE.The cumulative1- ......