【摘要】 目的 比较靶控输注异丙酚(target-controllde infusion，TCI)全凭静脉麻醉和异氟醚吸入麻醉两种不同方式在腹腔镜胆囊切除术(laparoscopic cholecystectomy，LC)应用中的临床效果。 方法 将30例择期行LC手术的患者随机分为两组。TCI组(T组)(n=15):设定诱导时靶浓度为4μg/ml，术中维持异丙酚靶浓度为3～3.5μg/ml。异氟醚组(I组)(n=15):采用3%异氟醚吸入诱导、1%～2.5%维持。术中监测心率(heart rate，HR)、收缩压(systolic blood pressure，SBP)、舒张压(dias-tolic blood pressure，DBP)、平均动脉压(mean arterial pressure，MAP)等指标。 结果 T组诱导时间显著短于I组(P<0.05)，术中T组生命体征维持相对平稳，术后苏醒T组明显优于I组。 结论 TCI全凭静脉麻醉方法用于LC术，术中血流动力学稳定，术后患者苏醒迅速，明显优于异氟醚吸入麻醉方法。

    【关键词】 胆囊切除术 腹腔镜 靶控输注 异丙酚 异氟醚

    Comparsion of anesthesia maintained by propofol target-controlled infusion with isoflurane inhalation for laparoscopic cholecystectomy

    Lin Daowei，Peng Shuling，Zheng Xiaojing

    Department of Anesthesiology，The Second Affiliated Hospital，Sun Yat-sen University，Guangzhou510120.

    【Abstract】 Objective To study the benefit of propofol with target-controlled infusion(TCI)for laparoscopic cholecystectomy(LC)in comparison with isoflurane inhalation.Methods Thirty patients scheduled for LC were ran-domized to two groups:propofol group(T-group)(n=15).The patients in T-group werre given TCI with the target concentration4μg/ml during induction and3～3.5μg/ml during maintenance.3%isoflurane during induction and1%～2.5%during maintenance were inhaled in I-group.SBP ......