薛军 罗小星 陈镜合 广州中医药大学第一附属医院急诊科，广州510405 中药新药与临床药理 1999 0 10 6


    关键词：开心胶囊；药理学；血液流变学；药物作用；心肌缺血；中药疗法；冠状动脉疾病；并发症 期刊 zyxyylcyl 0 药效与毒理学研究 fur -->


    

摘要：观察开心胶囊对糖尿病合并心肌缺血大鼠的血糖、血脂和血液流变学的影响。结果表明：开心胶囊(0.65g^. kg^-1 )可以显著降低模型大鼠甘油三酯、总胆固醇水平，提高高密度脂蛋白水平，并能改善模型大鼠血液流变学，进而起到改善心肌缺血的作用。

    中图分类号：R285.5；R543.3 文献标识码：A 文章编号：1003-9783(1999)06-0349-03

Effects of Kaixin Capsule on Blood Rheology of Rats with Myocardial Ischemia and Diabetes Mellitus

XUE Jun,LUO Xiao-xing,CHEN Jing-he

    (Postgraduate Student of Grade 98,Guangzhou University of TCM, The First Affiliated Hospital,

    Guangzhou University of TCM, Guangzhou 510405)

Abstract :Effects of Kaixin capsule on blood rheology in myocardial ischemia rats with diabetes mellitus were studied. The administration of Kaixin capsule at a dosage of 0.65 g/kg could significantly reduce plasma triglyceride and total cholesterol,elevate the blood level of high-density lipoprotein in model mice and improve blood rheology.The results suggest that Kaixin capsule is an effective preparation for improving the status of myocardial ischemia.

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