关键词:抗心磷脂抗体;乙型肝炎病毒感染
摘 要 为了解抗心磷脂抗体(ACA)在乙型肝炎病毒(HBV)感染中的流行情况,采用ELISA法对162例HBV感染者和102例正常对照者作ACA测定。结果表明,HBV感染者ACA阳性率(15.43%)与正常对照组(3.92%)相比有显著性升高(P<0.01);在HBV感染者中,肝功能异常者ACA阳性率明显高于肝功能正常者(P<0.01)。说明ACA可常见于乙型肝炎感染者,并可能与乙型肝炎的病情有关。
Anticardiolipin antibodies in patients with hepatitis B virus infection.
Chen Zhi ping,Xu Guocheng,Lin Rui,et al.
Guangxi Medical University,Nanning 530021
Abstract In order to study the prevalence of anticardiolipin antibodies (ACA) in hepatitis B virus (HBV) infection,ACA was determined in sera from 168 patients with HBV infection and 102 healthy controls by ELISA.The research showed that there was statistically significant difference between the positive rate of ACA in patients (15.43%)and the positive rate of ACA in control group(3.92%)(P<0.01).In addition,the positive rate of ACA in patients with abnormal liver function was higher than that in patients with normal liver function(P<0.01).The result suggests that ACA is frequently found in patients with HBV infection.ACA may be implicated in severity of hepatic injury.
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