Subject headings

Abstract

AIM To study the clinicalpeculiarities of patients infected with different genotypes of hepatitis C virus (HCV).

    METHODS Genotypes of HCV in 90 HCV-RNA-positive patients in Xuzhou area were examined.Clinical data of the patients were compared.

    RESULTS HCV Ⅱamountedto 78.9% (71/ 90), predominating over HCV Ⅲand HCV Ⅱ/ Ⅲwhich held 18.9% (17/ 90) and 2.2% (2/ 90) respectively inthe area. ALT level and ALT positivity rate were higher in HCV Ⅱthan in HCV Ⅲ(P<0.05) within a range of >200 U/ L. Anti-HCV OD value and anti-HCV positivity ratewhen its OD value was over 2, were lower in HCV Ⅱthan in HCV Ⅲ(P<0.05). Most jaundice patients (87%) were infected with HCVⅡ. No significantdifference was found in age, sex and transfusion experience between HCV Ⅱand HCV Ⅲpatients (P>0.05).

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