李晓凤 王亚兰 毋永娟 李晓凤(包头市第七医院肿瘤科 内蒙古自治区包头市014030)；王亚兰(包头市第七医院肿瘤科 内蒙古自治区包头市014030)；毋永娟(包头市第七医院肿瘤科 内蒙古自治区包头市014030) 中国肿瘤临床 2000 0 27 5


    关键词：生物治疗联合化疗；高聚生；恶性胸水；套管针置入 期刊 zgzllc 0 论著 fur -->


    

摘要 目的：观察高聚生联合化疗药物胸腔内灌注对 恶性胸水的疗效。方法：采用胸腔穿刺、置入长套 管针灌注高聚生及顺铂与单用顺铂疗效对照。结果 ：高聚生+顺铂组40例，有效率82.5%；化疗组顺铂36例 ，有效率47.2%(P<0.05)。结论：经长套管针置入灌注 生物制剂+化疗药物，疗效明显优于胸腔内单纯灌 注化疗药物，因此生物制剂高聚生经长套管针置入 胸腔内灌注不失为治疗恶性胸水的有效方法之一。

Clinical Observation on Malignant Pleural Effusion Treated by Intrapleural Catheterization and Infusion of Highly Agglutinative Staphylococcin (A Report of 40 Cases)

Li Xiaofeng Wang Yalan Wu Yongjuan
(Department of Medical Oncology, The Seventh Hospital of Baotou City, Baotou)

Abstract Purpose: To evaluate the therapeutic effects of infusing highly agglutinative staphylococcin (HAS) and combined- chemotherapeutic drugs into pleural cavity for treatment of malignant pleural effusion. Methods: At first the peural effusion was drained out from a intrapleural catheter and then infused the highly agglutinative staohylococcin plus cisplatin, and the control group was infused cisplatin alone, and their therapeutic effects were compared in a randomized trial. Results: The response rate of 40 cases of HAS group was 82.8% , whereas the response rate of the 36 cases of control group was 47.2% (P<0.05). Conclusion: The results showed that the effect of HAS is superior to that of the cisplatin alone and it may be one of the effective ways to control malignant pleural effusion.
Key Words Biological therapy Combined- chemotherapy Highly agglutinative staphylococcin Catheterization Malignant pleural effusion

恶性胸腔积液是晚期癌症的主要并发症 ......

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