摘要 为了探讨慢性肺原性心脏病(肺心病)急性发作期患者血清一氧化氮(NO)、脂质过氧化物丙二醛(MDA)及超氧化物岐化酶(SOD)水平的变化及其意义，选择38例肺心病患者测定其血清NO、MDA、SOD含量，并与25例正常人进行对比分析，结果显示：肺心病急性发作期患者血清NO、SOD明显降低，MDA明显增高(P<0.01～0.001)，提示：NO、MDA含量及SOD活性三者水平变化参与了肺心病的发生、发展过程。

Chen Qinmin

Second Guiyang People's Hospital, Guiyang, Guizhou, 550005

In order to evaluate the changes and expression of blood serum N0, SOD and MDA in patients with chronic pulmonary heart disease in acute attack stage, the content of blood NO, MDA and SOD in 38 cases were detected and compared to those in 25 normal individuals. It was found that blood serum NO, SOD decreased significantly in patients with pulmonary heart disease in acute attack stage, and MDA increased significantly (P<0.01～0.001). It indicated that the changes of NO, MDA and SOD were involved in the process of the growth and progressing of pulmonary disease.

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