关键词：肝肿瘤；栓塞化疗；介入治疗；乙醇；免疫因子
摘要 目的： 评价鸦胆子油-碘油“夹馅”栓塞法、瘤内注射乙醇与免疫因子联合介入治疗中晚期肝癌的临床疗效。方法： 37例失去手术机会的中晚期肝癌患者，分为两组：A组交替做经肝动脉鸦胆子油-碘油-抗癌药“夹馅”法栓塞化疗(TAE)及经皮无水乙醇癌灶内注射(PEI)，并联合局部应用免疫因子介入治疗；B组单纯用TAE治疗。结果： A组和B组的显效率、有效率、1年生存率分别为47%和10%、100%和90%、76%和30%，其差异有显著性；而两组的毒副反应无明显差异。A组17例患者中有7例获手术切除。结论： TAE+PEI+局部注射免疫因子的综合介入疗法，可能成为治疗中晚期HCC的一种新方法。
中国图书资料分类法分类号 R453
INTERVENTIONALTREATMENT OF ADVANCED HEPATOCELLULAR CARCINOMA WITH BRUCEA JAVANICA-LIPIODOL “SANDWICH” EMBOLIZATIONS AND INTRATUMORAL INJECTIONS OF ETHANOL AND IMMUNOCYTOKINES
Wei Bo,Liu Yuanwen,Jiang Yujie,et al
The First Hospital of Liuzhou City,Guangxi Province Liuzhou 545001
Abstract Objective: To evaluate theclinical effect of Brucea javanica-lipiodol “Sandwich” embolizations combined withintratumoral ethanol injections and immunocytokines injections on treatment of moderateand advanced primary hepaticellular carcinoma (HCC).Method: 37 cases ofmoderate and advanced stages of unresectable HCC were divided into two groups,17 patients(A group) were alternately treated with transcatheter arterial chemoembolization (TAE)with “sandwich” method of Brucea javanica-lipiodol-anticancer agents and subcutaneousethanol injection (PEI),combined with intratumoral injectins of immunocytokines,and 20patients (B group) were treated with TAE alone.Results: Partial response (PR),total efficacy rate,1-year survival rate of A and B group were 47% and 30%,100% and90%,76% and 30%,respectively,there was significant difference between two groups.Nostatistically significant difference was found in side effects between two groups.7 cases(41.1%) were resected from A group.Conclusion: Combined interventionaltherapy of TAE with PEI with intratumoral immunocytokines injections may be a new strategyfor advanced HCC.
......
您现在查看是摘要页，全文长 18371 字符。