关键词：重症肌无力危象；抢救；临床分析
摘要 目的： 复习重症肌无力(MG)危象抢救的体会及经验。方法： 对10年间抢救23例MG危象的临床特点、救治方法、并发症及死亡率进行总结分析。结果： 平均发病年龄约37岁，自MG发病至发生危象约2年，上呼吸道感染为最常见诱因。延髓肌麻痹需高度重视。应用呼吸机辅助呼吸平均为2周。并发症以肺炎及肺部感染为常见，激素治疗是主要手段之一。所有病人应用抗生素预防或治疗感染。死亡率为21.74%。结论： 及时插管甚至预防性气管切开，应用呼吸机，加强呼吸道管理，预防和治疗肺部感染，可改善危象的预后，明显降低死亡率。
中国图书资料分类法分类号 R746.1
ANALYSIS IN TREATMENT OF MYASTHENIC CRISIS
Zheng Jinou,Mo Xuean,Huang Wen
Department of Neurology,The Affiliated Hospital of Guangxi Medical University,Nanning 530021
Abstract Objective: To review theexperience in treatment and rescue of myasthenic crisis.Methods: Toanalyze the clinical feature,treatment and rescuse,complications and mortality in 23patients with MG crisis over a period of 10 years.Results: Median age ofonset of the first crisis was 37,and the median interval from onset of symptoms to thefirst crisis was 2 years.Upper respiratory infection was the most common precipitationfactor.Weakness of oropharyngeal muscles should arouse more attention.The time formechanical ventilation was two weeks.Pneumonia and pulmonary infection were commoncomplications.Treatment with corticosteroids was one of the main methods.Antibiotics wereused to prevent and treat infection in all patients.The mortality rate was 21.74%.Conclusion: Oncethere is prompt application of mechanical ventilation,improvement of respiratorycare,preventment and treatment of pulmonary infections,there will be improvemeat for theoutcomes in the future and decline the mortality rate.
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