董玲 李云谷 王和东 北京中医药大学 北京100029 北京中医药大学学报 1999 0 22 5


    关键词：克痹痛胶囊剂；药效动力学；药效指标；房室模型拟和；药代动力学参数 期刊 bjzyydxxb 0 中医药实验研究 fur -->


    

摘要： 采用药理效应法，以止痛效应(最大扭体次数的减少量)为药效指标，进行了克痹痛胶囊剂的药效动力学研究，考察该胶囊剂的体内代谢情况，通过计算机程序，求得相关参数，证明本品药效动力学模型为二室开放模型。

PharmacodynamicResearch on Analgesic Effect of Kebitong Capsule

Dong Ling (董 玲), Li Yungu (李云谷) ,Wang Hedong (王和东)

    (Beijing University of Traditional Chinese Medicine, Beijing100029)

ABSTRACT: The researchwas carried on with pharmacological effective method and analgesic effect (numberreduction of maximum body twisting) was taken as drug effect index. Observe internalmetabolism of the capsule, compute out the correlation parameter through computer program.It proved the capsule's pharmacodynamic model was two-compartment open model.

     KEY WORDS: Kebitong capsule; Pharmacodynamic; Drug effect index; Atrioventricular model of fit; Pharmacokineticsparameter

克痹痛胶囊剂是一种以制川乌为主药的纯中药制剂 ......

    百拇医药网 http://www.100md.com/html/DirDu/2005/07/04/66/61/79.htm

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