摘要： 采用大鼠肾毒血清性实验模型，分为凉血化瘀治疗组、补肾治疗组和空白对照组，各灌服8周后杀检，测定各组血液流变学指标并进行组间比较。结果表明：凉血化瘀治疗组各项血液流变学指标(全血粘度、血浆比粘度、红细胞压积、纤维蛋白原含量)均明显优于病理组，组间比较具有显著性差异；补肾组和病理组之间相比无显著性差异。说明凉血化瘀法对于实验性肾小球肾炎大鼠血液流变学指标的改善作用强于补肾法。

Effect of TCM Method Cooling the Blood and Dissipating BloodStasis and Kidney-Tonifying on Hemorrheology of the Rat with ExperimentalGlomerulonephritis

Peng Jianzhong Zhang Jiawei Wei Min et al.

    (Beijing University of Traditional Chinese Medicine, Beijing 100029)

ABSTRACT: Dividing the experimental nephrolyticserum rat models into 3 groups: treatment group with cooling the blood and dissipatingblood stasis method, group with kidney-tonifying method and the blank control group, afterfilling for 8 weeks put them to death and then assay the hemorrheology indices of eachgroup. The results show the hemorrheology indices of treatment group with cooling theblood and dissipating blood stasis method, which include whole blood viscosity, plasmacomparing viscosity, hematocrit and fibrinogen content, are all markedly better thanpathological group. The inter-group comparison also differs greatly. But there is noobvious difference between the group with kidney-tonifying method and the blank controlgroup. It indicates that the TCM method of cooling the blood and dissipating blood stasisis more effective than the kidney-tonifying method on improving the rat hemorrheologyindices with experimental glomerulonephritis.

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