关键词:胃舒颗粒;胃粘膜;氧自由基;大鼠
摘 要: 观察了胃舒颗粒对大鼠胃粘膜的保护作用,并对其作用机理进行探讨。结果表明:胃舒颗粒对消炎痛、酸性乙醇和水浸—束缚应激诱导的大鼠胃粘膜损伤具有明显的保护作用。这种粘膜保护作用与其提高胃粘膜清除氧自由基能力有关,而对胃液成分及胃壁结合粘液含量无明显影响。
Experimental Research of Weishu Granular onGastric Mucosa Protection
Wang Jing (王 晶),Hou Jiayu (侯家玉),LiuHengkuan (刘衡宽),et al.
(Beijing University of Traditional Chinese Medicine, Beijing 100029)
ABSTRACT: The protective effects of the WeishuGranular on the gas tric mucosa of rats were observed and the mechanism of action wasdiscussed. The results show that the Weishu Granular has a markedly protection on the gastric mu cosa injury induced by the indometacin, acidic ethanol and water immersion-encha ining. The protection correlates with enhancing the ability of the gastric muco sa toclear the oxygen free radical. It has no significant effects on the gastri c content andthe gastric folds bound mucus.
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