璇峰厛鐧诲綍
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关键词：虚喘证候；动物模型；治疗反证
导师：晁恩祥
摘 要： 在同一小鼠体上以木瓜蛋白酶雾化吸入造成肺气肿疾病模型，同时构建中医肾虚证，以此模拟肺肾两虚的中医虚喘证候。造模前后观察小鼠的耐力、耐寒能力，自由期三项指标SOD、GSH-PX、MDA的变化与临床一致；用调补肺肾方进行治疗有效，反证模型的可靠性。
CreatingAnimal Models for TCM Dyspnea Of Deficiency
Han Chunsheng (韩春生),Zhang hongchun (张洪春),YangDaowen (杨道文)
(Sino-Japanese Friendship Hospital, Beijing 100029)
ABSTRACT: Pneumonectasis by theaerosol inhalation spray of vela rdon and TCM syndrome of kidney-asthenia was induced onthe same mouse, in order to simulate the TCM dyspnea of deficiency type caused by astheniaof lun g and kidney . Observing the endurance, cold tolerance and changes of the threeparameters in free time which are SOD、GSH-PX and MDA, the results show the th reeparameters are in accordance with those in clinic. Then treat with the presc ription of“regulating and nourishing the lung and kidney” to prove the reliability of the model.
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