关键词:四物汤;电离辐射;红细胞免疫;骨髓干细胞;小鼠
摘 要: 用四物汤对辐射损伤小鼠进行治疗。结果表明:电离辐射对小鼠红细胞免疫功能及骨髓干细胞增殖能力有明显的抑制作用,应用四物汤治疗后红细胞免疫功能得到恢复,说明四物汤有较明显的增强红细胞免疫功能的作用。由骨髓干细胞增殖实验中可看出四物汤可使受照小鼠的骨髓干细胞增殖能力恢复正常。该研究为四物汤治疗辐射损伤引起的红细胞免疫功能及造血功能低下提供了实验依据。
分类号: R285.5
Effects of Siwu Decoctionon RBC Immunoadhesive Function and Stem Cell Multiplication
Zhang Ting, Tan Yunyu, Pan Yanshu
(Beijing University of Traditional Chinese Medicine, Beijing 100029)
Abstract: The effects of Siwudecoction on mouse model with radiation injury were investigated. The result indicatedthat ionized radiation could obviously suppress RBC immunoadhesive function and stem cellmultiplication. After treatment with Siwu decoction, the RBC immunoadhesive function andthe ability of stem cell multiplication in the irradiated mice were improved. This studyprovided scientific basis of using Siwu decoction for the treatment of radiogenicimmunodeficiency.
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