舒波 窦晓光 刘沛 黄敦武 王兆荃 黄敦武 解放军第202医院；舒波 窦晓光 刘沛 王兆荃 中国医科大学第二临床学院传染科，沈阳 110003 中国医科大学学报 1999 0 28 5


    关键词：输血传播病毒；DNA；聚合酶链式反应；原因不明性肝炎 期刊 zgykdxxb 0 临床医学 fur -->


    

摘要 目的： 调查原因不明性肝炎的TTV感染状况。方法：设计TTV基因的特异性引物，应用PCR反应检测48例原因不明性肝炎血清中的TTV DNA。结果：48例原因不明性肝炎中13例TTV DNA阳性(27.1%)，其中急性肝炎9例，慢性肝炎3例，亚急性重型肝炎1例。结论：TTV感染是原因不明性肝炎的致病因子，TTV感染能引起急性、慢性以及重型肝炎。

Detection of TTV Infection and Clinical Investigation in Patientswith Hepatitis of Unknown Etiology

Shu Bo, Dou Xiaoguang, Liu Pei, et al

Department of Infectious Diseases, The Second Clinical College, China Medical Unviersity, Shenyang, 110003

ABSTRACT Objective: We investigated investigate the presence of TTV infection among patients with hepatitis of unknown etiology. Methods: Forty-eight serum samples from patients with hepatitis of unknown etiology were detected for TTV DNA by PCR methods. Results: The positive rate of TTV DNA accounted for 27.1% (13/48) in patients with hepatitis of unknown etiology. Among 13 patients with TTV DNA positive response, 7 were acute hepatitis, 5 were chronic hepatitis and 1 was subfulminant hepatitis. Conclusion: TTV infection could be associated with occurence of hepatitis, and could result in acute, chronic and fulminant hepatitis.

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