【摘要】 目的 为了解异丙肾上腺素倾斜试验(ITTT)加硝酸异山梨醇酯舌下含化诊断血管迷走性晕厥的价值。方法 96例血管迷走性晕厥病人及72例无晕厥病史的健康人分成ITTT加服硝酸异山梨醇酯舌下含组(ITTT+ID)和单纯ITTT组。结果 ITTT+ID组敏感性(86.5%与67.5%，P<0.01)明显高于ITTT组，前者诱发晕厥所需时间(4.53±2.86分钟与6.27±4.11分钟，P<0.05)及实验总时程(24.84±5.15分钟与35.70±6.28分钟，P<0.01)明显短于ITTT组。结论 ITTT加硝酸异山梨醇酯舌下含化是一种敏感性高、特异性强、节时的诊断血管迷走性晕厥的一种方法。

    The value of sublingual isosorbide dinitrate before head-uptilt test for diagnosis of neurocardiogenic mediated syncope Zeng Chunyu, Liu Guangyao, Wang Xukai, et al. Department ofCardiology, Daping Hospital, Third Military Medical University, PLA, Chongqing 400042

    【Abstract】 Objective To assess the valueof sublingual isosorbide dinitrate administration before isoproterenol tilt table test(ITTT) as a simple practical test for diagnosis of neurocardiogenic mediated syncope(NMS). Methods 96 patients with NMS and 72 healthycontrols without syncope were divided into two groups: sublingual isosorbide dinirateadministration before ITTT (ITTT+ID) and only ITTT. Results The ITTT+ID group has higher sensitivity (86.5% vs 67.5%;P<0.01) than ITTT group in diagnosis of NMS. The time induced syncope (4.53±2.86 minvs 6.27±4.11min; P<0.05) and the duration of the test (24.84±5.15min vs 35.70±6.28min;P<0.01) were shorter in ITTT+ID group than that in ITTT group. Conclusion Sublingual isosorbide dinitrate administration before ITTT is asimple practical test with high sensitivity, powerful specificity and short duration indiagnosis of NMS.

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