目的 分析系统性红斑狼疮(SLE)患者的死因，目的在降低其病死率。方法 对465例SLE患者中的90例死者死因进行分析。结果 最主要死因是SLE本身40例(44.44%)，其次是感染30例(33.33%)，心血管疾病12例(13.33%)。SLE与感染致死较常发生于年轻患者。SLE死亡多发生在诊断后的头三年。结论 SLE死亡最主要原因是SLE本身，故对SLE活动应积极治疗，但不能过度，以免引发感染而死亡。

    Analysis of causes of death in 90 patients with systemic lupus erythematosus Mai Ciguang^* , Zhang Daoyou, Ye Rengao. ^* Guangzhou Second People′s Hospital, Guangzhou 510150

    Objective To analyse the causes of death in a cohort of patients with systemic lupus erythematosus (SLE) and to decrease the mortality of SLE. Methods 90 patients died in a cohort of 465 patients with SLE were analysed. Results SLE itself was the most common cause of death occurring in 40 patients (44.44%), followed by infection (n=30, 33.33%), cardiovascular disease (n=12,13.33%). Deaths due to SLE and infection were more common among younger patients. The risk of death due to SLE was greatest within the first 3 years after diagnosis. Conclusion The most common death cause of SLE is SLE itself, so it should be treated positively, but excessive medication must be avoided, otherwise infection would occur, leading to a increase of the mortality.

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