丁惠国 闫惠萍 孟欣 金瑞 胡中杰 刘素珍 闵福援 100054 北京佑安医院 中华消化内镜杂志 1999 0 16 4


    关键词：肝硬化；胃粘膜病变；Hp感染 期刊 zhxhnjzz 0 论 著 fur -->


    

摘要 目的 探讨Hp感染在肝硬化胃粘膜病变中的意义。方法 接受内镜检查的肝硬化患者50例，非肝硬化患者27例；采用快速尿素酶试验、Warthin-starry银染色、血清学方法诊断Hp感染。结果 肝硬化患者胃粘膜Hp感染率、血清抗Hp基因重组抗原IgG、Hp菌体抗原IgG及IgA阳性率分别为30%、78%、87.2%、29.4%，与非肝硬化患者比较差异无显著性。肝硬化患者合并与不合并胃粘膜病变者Hp感染率也无明显差异(P>0.05)。结论 肝硬化患者Hp感染率与普通人群相似，Hp感染不是肝硬化患者胃粘膜病变主要致病因素。

    

Helicobacter pylori infection in cirrhotic patient with gastric mucosal lesion.

DING Huiguo,YAN Huiping,MONG Xin,et al.

    Liver Unit of Beijing You An Hospital,Beijing 100054.

Abstract Objective The role of Helicobacter pylori(Hp) infection in gastropathy associated with liver cirrhosis was studied.Methods Gastroscopy was performed on 50 cirrhotic and 27 non-cirrhotic patients.Hp infection was verified by rapid urease test,Warthin-Starry silver stainning and serological reactions.Results In terms of Hp infection incidence ,serum Hp CagA+VacA IgG antibody,Hp IgG and IgA antibodies,no significant difference was found between patients with and without cirrhosis,nor between cirrhotic patients with and without gastropathy.Conclusion The incidence of Hp infection in the cirrhotic appeared similar to general population.Hp infection might not be the main etiological factor for gastropathy seen in cirrhotic patient.

    Key words Liver cirrhosis Gastric mucosal lesion Helicobacter pylori infection

幽门螺杆菌(Helicobacter pylori,Hp)感染与消化道疾病有密切关系 ......