吴惠生 聂玉强 李瑜元 王红 黎庆宁 510180 广州市第一人民医院消化内科 中华消化内镜杂志 1999 0 16 4


    关键词：食管静脉曲张出血；生长抑素；硬化剂；套扎治疗 期刊 zhxhnjzz 0 论 著 fur -->


    

摘要 目的 观察内镜下治疗和生长抑素(SS)联合对食管静脉曲张出血的短期止血效果。方法 病人分二组，SS组在急诊内镜前后连续用SS 5天；联合组在SS基础上加行内镜下硬化剂或套扎，但内镜48小时后停用SS。结果 硬化剂37例和套扎32例共计69例的联合组与64例SS组间具可比性。在需气囊压迫、最初止血率、再出血率和死亡率方面，联合组的效果显著优于SS组。二组间的输出血量差异不显著。结论 与单纯SS治疗相比，内镜治疗和SS联合可减少气囊压迫的需求，提高止血率，降低再出血率，进而降低死亡率。

    

Somatostatin with or without endoscopic intervention for

    esophageal variceal bleeding

WU Huisheng ,NIE Yuqiang,LI Yuyuan,et al.

    Department of Gastroenterology,First Municipal People's Hospital of Guangzhou,510180

Abstract Objective The early effect of using somatostation(SS) alone was compared with that associated with endoscopic intervention for bleeding from esophageal varices(EV).Methods 133 patients with liver cirrhosis and EV bleeding were assigned to use of SS alone(n＝64), 250 μg bolus injection and 250μg/h i.v. infusion for 5 days and to the endoscopic sclerosis(n＝37) or band ligation(n＝32) followed by 250μg/h i.v.dripping of SS for 2 days.Results It showed that patients receiving sclerotic injection and band ligation had better results in immediate hemostasis ,less tamponade assistance as well as lower rebleeding and mortality rates.No difference was found in amount of blood transfusion between the two therapies.Conclusion The combination of SS and endoscopic intervention justified its preference to the single application of SS.

    Key words Variceal bleeding Somatostatin Sclerotherapy Endoscopic ligation

是否内镜下止血与药物联合的方法提高食管静脉曲张出血的治疗效果 ......